Human IgG2 Fc

The fragment crystallizable region (Fc region) is the tail region of an antibody that interacts with cell surface receptors called Fc receptors and some proteins of the complement system. This property allows antibodies to activate the immune system. In IgG, IgA and IgD antibody isotypes, the Fc region is composed of two identical protein fragments, derived from the second and third constant domains of the antibody's two heavy chains; IgM and IgE Fc regions contain three heavy chain constant domains (CH domains 2–4) in each polypeptide chain. The Fc regions of IgGs bear a highly conserved N-glycosylation site. Glycosylation of the Fc fragment is essential for Fc receptor-mediated activity. The N-glycans attached to this site are predominantly core-fucosylated diantennary structures of the complex type. In addition, small amounts of these N-glycans also bear bisecting GlcNAc and a-2,6 linked sialic acid residues.

Human IgG2 Fc Target Details

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Products

Antibodies (11)

Proteins (3)

Type

Primary (11)

Recombinant (3)

Target

Human IgG2 Fc (14)

Reactivity

Human (11)

Application

IHC (7)

IHC-Fr (7)

WB (9)

Flo (2)

ELISA (9)

ELISPOT (2)

FLISA (4)

ICC (5)

IP (1)

Purif (1)

SPR (1)

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Host

mouse (11)

Isotype

IgG1 (9)

IgG1,k (2)

Clonality

monoclonal mc (11)

Clone

31-7-4 (6)

HP6002 (5)

Format

AP Conjugated (2)

Biotin Conjugated (2)

FITC Conjugated (2)

HRP Conjugated (1)

PE Conjugated (2)

Unconjugated (2)

Publications

No (14)

Species

Human (3)

Source

Human Cells (1)

Mammalian Cells (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (3)

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Human IgG2 Fc Antibody (clone HP6002, Biotin) LS-C351388

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (Biotin) (HP6002) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, IHC-Fr, WB

Format:

Biotin Conjugated

Price:

0.5 mg/$365

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Human IgG2 Fc Antibody (clone HP6002) LS-C351386

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (HP6002) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, IHC-Fr, WB

Format:

Unconjugated

Price:

0.5 mg/$321

Select

Human IgG2 Fc Antibody (clone 31-7-4, Biotin) LS-C351383

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (Biotin) (31-7-4) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, IHC-Fr, WB

Format:

Biotin Conjugated

Price:

0.5 mg/$365

Select

Human IgG2 Fc Antibody (clone 31-7-4, AP) LS-C351377

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (AP) (31-7-4) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

AP Conjugated

Price:

1 ml/$391

Select

Human IgG2 Fc Antibody (clone 31-7-4) LS-C351376

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (31-7-4) Antibody

Reactivity:

Human

Applications:

ELISA, ICC, IHC, WB

Format:

Unconjugated

Price:

0.5 mg/$321

Select

Human IgG2 Fc Antibody (clone 31-7-4, HRP) LS-C351381

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (HRP) (31-7-4) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

HRP Conjugated

Price:

1 ml/$383

Select

Human IgG2 Fc Antibody (clone 31-7-4, PE) LS-C351385

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (PE) (31-7-4) Antibody

Reactivity:

Human

Applications:

FLISA

Format:

PE Conjugated

Price:

0.1 mg/$400

Select

Human IgG2 Fc Antibody (clone 31-7-4, FITC) LS-C783647

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (FITC) (31-7-4) Antibody

Reactivity:

Human

Applications:

ELISA, ELISPOT, FLISA, Flo, ICC, WB

Format:

FITC Conjugated

Price:

0.5 mg/$383

Select

Human IgG2 Fc Antibody (clone HP6002, AP) LS-C351389

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (AP) (HP6002) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-Fr, WB

Format:

AP Conjugated

Price:

1 ml/$391

Select

Human IgG2 Fc Antibody (clone HP6002, FITC) LS-C783652

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (FITC) (HP6002) Antibody

Reactivity:

Human

Applications:

ELISA, ELISPOT, FLISA, Flo, IHC-Fr, IP, Purif, SPR, WB

Format:

FITC Conjugated

Price:

0.5 mg/$383

Select

Human IgG2 Fc Antibody (clone HP6002, PE) LS-C351391

Antibody:

Human IgG2 Fc Mouse anti-Human Monoclonal (PE) (HP6002) Antibody

Reactivity:

Human

Applications:

FLISA

Format:

PE Conjugated

Price:

0.1 mg/$400

Select

Human IgG2 Fc Protein (Recombinant) (Glu99-Lys326) - LS-G138584

Source:

Mammalian Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.7 kDa

Price:

10 µg/$233; 50 µg/$277

Select

Human IgG2 Fc Protein (Recombinant) (Val104-Lys326) - LS-G138585

Source:

Mammalian Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25.1 kDa

Price:

10 µg/$233; 50 µg/$277

Select

Human IgG2 Fc Protein (Recombinant) (Glu99-Lys327) - LS-G97571

Source:

Human Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

25 kDa

Price:

100 µg/$418; 1 mg/$1,400

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