HTRA1

HtrA serine peptidase 1

Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space. Regulates the availability of insulin-like growth factors (IGFs) by cleaving IGF-binding proteins. Inhibits signaling mediated by TGF-beta family members. This activity requires the integrity of the catalytic site, although it is unclear whether TGF-beta proteins are themselves degraded. By acting on TGF-beta signaling, may regulate many physiological processes, including retinal angiogenesis and neuronal survival and maturation during development. Intracellularly, degrades TSC2, leading to the activation of TSC2 downstream targets.

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Products

Antibodies (50)

Type

Primary (50)

Target

HTRA1 (50)

Reactivity

Human (49)

Mouse (13)

Rat (6)

Bovine (4)

Chimpanzee (3)

Dog (1)

E. coli (16)

Gibbon (3)

Monkey (3)

Pig (3)

Application

IHC (16)

IHC-P (4)

WB (50)

ELISA (12)

ICC (1)

IF (8)

Peptide-ELISA (1)

Host

rabbit (50)

Isotype

IgG (17)

Clonality

polyclonal pc (50)

Format

APC (3)

APC Conjugated (5)

Azide-free (2)

Biotin Conjugated (6)

Cy3 Conjugated (3)

Cy7 Conjugated (3)

FITC Conjugated (6)

HRP Conjugated (6)

PE Conjugated (5)

Unconjugated (16)

Epitope

aa10-146 (8)

aa204-364 (8)

aa304-442 (8)

aa116-147 (7)

aa381-412 (7)

aa122-171 (4)

aa234-249 (2)

Publications

No (49)

Yes (1)

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HTRA1 Antibody (aa116-147) LS-C98878

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa116-147) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

200 µl/$393

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HTRA1 Antibody (aa122-171) LS-C146185

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa122-171) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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HTRA1 Antibody (aa234-249) LS-C190914

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa234-249) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$634

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HTRA1 Antibody LS-C781555

Antibody:

HTRA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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HTRA1 Antibody (aa204-364) LS-C294536

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa204-364) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$597; 2 ml/$826; 5 ml/$1,352

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HTRA1 Antibody (aa204-364, Biotin) LS-C297382

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa204-364) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$329; 200 µl/$381; 500 µl/$550; 1 ml/$654; 2 ml/$890; 5 ml/$1,487

• Unconjugated
• Biotin

• Unconjugated
• Biotin

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HTRA1 Antibody (aa116-147) LS-C327589

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa116-147) Antibody

Reactivity:

Mouse, Human

Applications:

IF, IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

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HTRA1 Antibody (aa116-147, Biotin) LS-C278267

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa116-147) (Biotin) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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HTRA1 Antibody (aa116-147, FITC) LS-C278268

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa116-147) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

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HTRA1 Antibody (aa116-147, APC) LS-C278266

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa116-147) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

HTRA1 Antibody (aa116-147, Azide-free, HRP) LS-C278269

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa116-147) (Azide-free) (HRP) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

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HTRA1 Antibody (aa116-147, PE) LS-C278270

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa116-147) (PE) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, IF, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

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HTRA1 Antibody LS-C832624

Antibody:

HTRA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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HTRA1 Antibody LS-C662735

Antibody:

HTRA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

10 µg/$318; 100 µg/$470

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HTRA1 Antibody (aa381-412) LS-C327588

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa381-412) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

HTRA1 Antibody (aa381-412, Biotin) LS-C278273

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa381-412) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

HTRA1 Antibody (aa381-412, FITC) LS-C278274

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa381-412) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

HTRA1 Antibody (aa381-412, APC) LS-C278271

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa381-412) (APC) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

HTRA1 Antibody (aa381-412, PE) LS-C278276

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa381-412) (PE) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

PE Conjugated

Price:

200 µl/$952

Select

HTRA1 Antibody (aa381-412, Azide-free, HRP) LS-C278275

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa381-412) (Azide-free) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• PE
• HRP, Azide-free

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • PE
  • HRP, Azide-free

Select

HTRA1 Antibody LS-C803456

Antibody:

HTRA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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HTRA1 Antibody LS-C782094

Antibody:

HTRA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

100 µg/$575

Select

HTRA1 Antibody (aa234-249) LS-C148634

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa234-249) Antibody

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

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HTRA1 Antibody (aa10-146) LS-C374982

Antibody:

HTRA1 Rabbit anti-Human Polyclonal (aa10-146) Antibody

Reactivity:

E. coli, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$349; 200 µl/$408; 500 µl/$609; 1 ml/$762; 2 ml/$999; 5 ml/$1,729

Select

HTRA1 Antibody LS-C747080

Antibody:

HTRA1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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