HTR2C / 5-HT2C Receptor

5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances, including ergot alkaloid derivatives, 1-2,5,-dimethoxy-4-iodophenyl-2-aminopropane (DOI) and lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca2+ ions from intracellular stores. Regulates neuronal activity via the activation of short transient receptor potential calcium channels in the brain, and thereby modulates the activation of pro-opiomelacortin neurons and the release of CRH that then regulates the release of corticosterone. Plays a role in the regulation of appetite and eating behavior, responses to anxiogenic stimuli and stress. Plays a role in insulin sensitivity and glucose homeostasis.

☰ Filters

Products

Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

HTR2C / 5-HT2C Receptor (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Select

HTR2C / 5-HT2C Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122943

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.6 kDa

Price:

100 µg/$710

Select

Human HTR2C / 5-HT2C Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74133

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.6 kDa

Price:

20 µg/$215

Select

Human HTR2C / 5-HT2C Receptor Protein (Recombinant GST, N-terminus) (aa1-52) - LS-G58919

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

Viewing 1-3 of 3 product results

(0) Selected Add Selected To Cart Compare Selected Email Selected Clear Selected Top Of Search

---

Filtered By:

Products: Proteins

Clear Filters

If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.