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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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HTR1B / 5-HT1B Receptor

5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for ergot alkaloid derivatives, various anxiolytic and antidepressant drugs and other psychoactive substances, such as lysergic acid diethylamide (LSD). Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling inhibits adenylate cyclase activity. Arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Regulates the release of 5-hydroxytryptamine, dopamine and acetylcholine in the brain, and thereby affects neural activity, nociceptive processing, pain perception, mood and behavior. Besides, plays a role in vasoconstriction of cerebral arteries.

Gene Name: 5-hydroxytryptamine (serotonin) receptor 1B, G protein-coupled
Family/Subfamily: GPCR , Serotonin
Synonyms: HTR1B, 5-HT-1B, 5-HT-1D-beta, 5-HT1B, 5-HT1b receptor, 5-HT1DB, 5HT1B Receptor, HTR1DB, Serotonin 5-HT-1b receptor, Serotonin receptor 1B, Serotonin 1b receptor, HTR1D2, Serotonin 1D beta receptor
Target Sequences: NM_000863 NP_000854.1 P28222

Filtered by: None
Target
HTR1B / 5-HT1B Receptor (39)
Reactivity
Human (38)
Mouse (18)
Rat (18)
Bat (8)
Bovine (8)
Chicken (1)
Chimpanzee (3)
Dog (8)
Gibbon (3)
Guinea pig (8)
Hamster (8)
Horse (1)
Monkey (8)
Pig (7)
Rabbit (8)
Xenopus (1)
Application
IHC (18)
IHC-P (15)
WB (22)
ELISA (11)
IF (6)
Peptide-ELISA (5)
Host
rabbit (37)
mouse (1)
goat (1)
Isotype
IgG (21)
IgG1 (1)
Clonality
monoclonal mc (1)
polyclonal pc (38)
Format
AP Conjugated (3)
APC Conjugated (3)
Azide-free (3)
Biotin Conjugated (4)
FITC Conjugated (4)
HRP Conjugated (4)
PE Conjugated (3)
Unconjugated (18)
Epitope
aa225-253 (8)
Cytoplasmic Domain (7)
Internal (7)
N-Terminus (4)
aa8-26 (2)
180-260 aa, Internal (1)
230-310 aa, Internal (1)
aa179-228 (1)
aa201-250 (1)
aa256-305 (1)
aa261-310 (1)
aa372-382 (1)
Publications
No (39)
Showing 1-25 of 39 results

PathPlus™ HTR1B / 5-HT1B Receptor Antibody (Cytoplasmic Domain) LS-A598
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
Unconjugated
100µg 100µl 1mg/ml  $425.00
Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Vascular Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Cytoplasmic Domain, Biotin) LS-A106105
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Cytoplasmic Domain, FITC) LS-A106106
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Cytoplasmic Domain, AP) LS-A106103
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Cytoplasmic Domain, APC) LS-A106104
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Rabbit, Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Pig, Bat, Human
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human vascular smooth muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Internal) LS-A586
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
Unconjugated
50µg 50µl 1mg/ml  $425.00
Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-5HT1B Receptor antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Internal, Biotin) LS-A106075
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
Biotin Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-5HT1B Receptor antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Internal, FITC) LS-A106076
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
FITC Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-5HT1B Receptor antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Internal, AP) LS-A106073
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
AP Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-5HT1B Receptor antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Internal, APC) LS-A106074
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
APC Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-5HT1B Receptor antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Internal, Azide-free, HRP) LS-A106077
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
HRP Conjugated, Azide-free
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-5HT1B Receptor antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

IHC-plus™ HTR1B / 5-HT1B Receptor Antibody (Internal, PE) LS-A106078
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
Human, Monkey
IHC, IHC-P
PE Conjugated
100µl  $650.00
Anti-5HT1B Receptor antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-5HT1B Receptor antibody IHC of human vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

HTR1B / 5-HT1B Receptor Antibody LS-C124520
Mouse Monoclonal (IgG1) to Human HTR1B / 5-HT1B Receptor
Human
IHC
Unconjugated
100µg  $650.00

HTR1B / 5-HT1B Receptor Antibody (180-260 aa, Internal) LS-C386165
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

HTR1B / 5-HT1B Receptor Antibody (N-Terminus) LS-C30931
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Human
WB
Unconjugated
100µl 0.5mg/ml  $325.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

HTR1B / 5-HT1B Receptor Antibody (N-Terminus, FITC) LS-C481552
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Human, Chimpanzee, Gibbon
WB
FITC Conjugated
100µl 1mg/ml  $335.00
HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

HTR1B / 5-HT1B Receptor Antibody (aa8-26) LS-C611
Rabbit Polyclonal (IgG) to Rat HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
WB
Unconjugated
100µg 200µl 0.5mg/ml  $335.00
Western blot of 5-HT1BR in human brain lysate with anti-5-HT1BR pcAb. A protein band of approximate molecular weight of 40-41kD was detected.

HTR1B / 5-HT1B Receptor Antibody (aa372-382) LS-C55451
Goat Polyclonal to Human HTR1B / 5-HT1B Receptor
Xenopus, Chicken, Bovine, Rabbit, Mouse, Dog, Guinea pig, Bat, Rat, Hamster, Horse, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100µg 0.5mg/ml  $405.00
Antibody (2 ug/ml) staining of Human Brain lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
HTR1B / 5-HT1B Receptor antibody (1µg/ml) staining of Human Cerebellum (A) and Mouse spinal cord (B) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

HTR1B / 5-HT1B Receptor Antibody (aa261-310) LS-C120543
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunofluorescence analysis of A549 cells, using HTR1B Antibody. The picture on the right is blocked with the synthesized peptide.
Western blot analysis of lysates from HepG2 and MCF-7 cells, using HTR1B Antibody. The lane on the right is blocked with the synthesized peptide.

HTR1B / 5-HT1B Receptor Antibody (aa179-228) LS-C200060
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Western blot analysis of the lysates from HepG2 cells using 5-HT-1B antibody.

HTR1B / 5-HT1B Receptor Antibody LS-C804614
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunohistochemistry Image
Immunofluorescence Image

PathPlus™ HTR1B / 5-HT1B Receptor Antibody LS-A10705
Rabbit Polyclonal to Human HTR1B / 5-HT1B Receptor
IHC-P
Unconjugated
100µg 100µl 1mg/ml  $425.00
Human Liver, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate, Smooth Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)

HTR1B / 5-HT1B Receptor Antibody (230-310 aa, Internal) LS-C386163
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
50µl 1mg/ml  $235.00; 100µl 1mg/ml  $265.00; 200µl 1mg/ml  $335.00

HTR1B / 5-HT1B Receptor Antibody (aa201-250) LS-C291270
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
IF, IHC, Peptide-ELISA
Unconjugated
50µl 1mg/ml  $265.00; 100µl 1mg/ml  $325.00
Immunohistochemistry analysis of paraffin-embedded human brain tissue, using 5-HT-1B Antibody. The picture on the right is blocked with the synthesized peptide.
Immunofluorescence analysis of HeLa cells, using 5-HT-1B Antibody. The picture on the right is blocked with the synthesized peptide.

HTR1B / 5-HT1B Receptor Antibody LS-C809430
Rabbit Polyclonal (IgG) to Human HTR1B / 5-HT1B Receptor
Mouse, Rat, Human
ELISA, IF, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Immunofluorescence Image
Western blot Image
Showing 1-25 of 39 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).