HTR1A / 5-HT1A Receptor

5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various drugs and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling inhibits adenylate cyclase activity and activates a phosphatidylinositol-calcium second messenger system that regulates the release of Ca2+ ions from intracellular stores. Plays a role in the regulation of 5-hydroxytryptamine release and in the regulation of dopamine and 5-hydroxytryptamine metabolism. Plays a role in the regulation of dopamine and 5-hydroxytryptamine levels in the brain, and thereby affects neural activity, mood and behavior. Plays a role in the response to anxiogenic stimuli.

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Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

HTR1A / 5-HT1A Receptor (4)

Publications

No (4)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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HTR1A / 5-HT1A Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123135

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.9 kDa

Price:

100 µg/$494

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Human HTR1A / 5-HT1A Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74127

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

45.9 kDa

Price:

20 µg/$150

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Human HTR1A / 5-HT1A Receptor Protein (Recombinant GST, N-terminus) (aa1-36) - LS-G58914

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human HTR1A / 5-HT1A Receptor Protein (Recombinant GST) (Full Length) - LS-G28947

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.5 kDa

Price:

10 µg/$479; 25 µg/$670

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