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HSPBP1
HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1
Inhibits HSPA1A chaperone activity by changing the conformation of the ATP-binding domain of HSPA1A and interfering with ATP binding. Interferes with ubiquitination mediated by STUB1 and inhibits chaperone-assisted degradation of immature CFTR.
| Gene Name: | HSPA (heat shock 70kDa) binding protein, cytoplasmic cochaperone 1 |
| Synonyms: | HSPBP1, Hsp70 interacting protein, Hsp70-binding protein 1, Hsp70-interacting protein 1, HSPBP, Hsp70-binding protein 2, Hsp70 binding protein 1, HspBP2, FES1, Hsp70-interacting protein 2 |
| Target Sequences: | NM_012267 NP_036399.3 Q9NZL4 |
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