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HSP90B1 / GP96 / GRP94

heat shock protein 90kDa beta (Grp94), member 1

Molecular chaperone that functions in the processing and transport of secreted proteins. When associated with CNPY3, required for proper folding of Toll-like receptors (By similarity). Functions in endoplasmic reticulum associated degradation (ERAD). Has ATPase activity.

Gene Name: heat shock protein 90kDa beta (Grp94), member 1
Synonyms: HSP90B1, ECGP, Endoplasmin, gp96 homolog, gp96, GRP-94, GRP94, Tumor rejection antigen 1, TRA1
Target Sequences: NM_003299 NP_003290.1 P14625

Publications (2)

1
Endoplasmic reticulum-resident chaperones modulate the inflammatory and angiogenic responses of endothelial cells. R Tsaryk, N M Bartholomä, N Simiantonaki, L Anspach, K Peters, C Heilmann, C J Kirkpatrick, F Pröls. The British journal of dermatology. 2015 August;173:416-27. [Full Text Article] [PubMed:25832777] Related Antibodies: LS-B3243.
2
Paternal exposure to testis cancer chemotherapeutics alters sperm fertilizing capacity and affects gene expression in the eight-cell stage rat embryo. J Maselli, B F Hales, B Robaire. Andrology. 2014 March;2:259-66. [Full Text Article] [PubMed:24478030]

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Products
Proteins (12)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (7)
HSP90B1 / GP96 / GRP94 (12)
No (12)
6His, N-terminus (2)
GST (2)
His (2)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (10)
Mouse (1)
293T Cells (1)
E. coli (5)
HEK 293 Cells (4)
Wheat Germ Extract (2)
Purified (4)
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HEK 293 Cells
6His, N-terminus
93 kDa
100 µg/$298
HSP90B1 / GP96 / GRP94 Protein - Recombinant Heat Shock Protein 90kDa Beta 1 (HSP90b1) by SDS-PAGE
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E. coli
His, N-Terminal
32.1kDa
10 µg/$287; 50 µg/$482; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
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E. coli
None
94.4 kDa
2 µg/$329; 10 µg/$412; 1000 µg/$5,092
HSP90B1 / GP96 / GRP94 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
92.47 kDa
100 µg/$494
HSP90B1 / GP96 / GRP94 Protein - 12.5% SDS-PAGE of human TRA1 stained with Coomassie Blue
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Wheat Germ Extract
GST
57.97 kDa
10 µg/$479; 25 µg/$670
HSP90B1 / GP96 / GRP94 Protein - 12.5% SDS-PAGE of human TRA1 stained with Coomassie Blue
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Wheat Germ Extract
GST
60.28 kDa
10 µg/$479; 25 µg/$670
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E. coli
His
93.2 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
Select
HEK 293 Cells
6His, N-terminus
93 kDa
200 µl/$283
HSP90B1 / GP96 / GRP94 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
92.47 kDa
20 µg/$150
HSP90B1 / GP96 / GRP94 Protein - Purified recombinant protein HSP90B1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
90.1 kDa
20 µg/$1,107
HSP90B1 / GP96 / GRP94 Protein
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E. coli
His
100 µg/$511; 500 µg/$1,348; 20 µg/$311
HSP90B1 / GP96 / GRP94 Protein - Recombinant Heat Shock Protein 90kDa Beta 1 By SDS-PAGE
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E. coli
His-T7
32.1 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).