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HSD3B1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
3-beta-HSD is a bifunctional enzyme, that catalyzes the oxidative conversion of Delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. The 3-beta-HSD enzymatic system plays a crucial role in the biosynthesis of all classes of hormonal steroids. Efficiently catalyzes the transformation of pregnenolone to progesterone, 17-alpha-hydroxypregnenolone to 17-alpha-hydroxyprogesterone, DHEA to 4-androstenedione, dihydrotestosterone to 5-alpha-androstane-3 beta,17 beta-diol, dehydroepiandrosterone to androstenedione and 5-alpha-androstan-3 beta,17 beta-diol to 5-alpha-dihydrotestosterone.
| Gene Name: | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 |
| Synonyms: | HSD3B1, 3BETAHSD, 3-beta-HSD I, 3BH, HSD3B, HSDB3A, HSDB3, Steroid Delta-isomerase, Trophoblast antigen FDO161G, Progesterone reductase, SDR11E1 |
| Target Sequences: | NM_000862 NP_000853.1 P14060 |
Publications (3)
1
Isolation of fetal trophoblast cells from peripheral blood of pregnant women. Mueller UW, Hawes CS, Wright AE, Petropoulos A, DeBoni E, Firgaira FA, Morley AA, Turner DR, Jones WR. Lancet. 1990 336:197-200. (ICC)
[PubMed:1973769]
2
Dynamic changes in the expression of relaxin-like factor (INSL3), cholesterol side-chain cleavage cytochrome p450, and 3beta-hydroxysteroid dehydrogenase in bovine ovarian follicles during growth and atresia. Irving-Rodgers HF, Bathgate RA, Ivell R, Domagalski R, Rodgers RJ. Biology of reproduction. 2002 66:934-43. (IHC; Bovine)
[PubMed:11906911]
3
Cholesterol side-chain cleavage cytochrome P450 and 3beta-hydroxysteroid dehydrogenase expression and the concentrations of steroid hormones in the follicular fluids of different phenotypes of healthy and atretic bovine ovarian follicles. Irving-Rodgers HF, Krupa M, Rodgers RJ. Biology of reproduction. 2003 69:2022-8.
[PubMed:12930727]
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(30)
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(27)
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(37)
HSD3B1 Mouse anti-Human Monoclonal (3C11-D4) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
HSD3B1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human, Monkey
WB
Unconjugated
100 µl/$424
HSD3B1 Rabbit anti-Human Polyclonal (aa1-290) Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
HSD3B1 Goat anti-Human Polyclonal (aa362-373) Antibody
Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
HSD3B1 Mouse anti-Human Monoclonal (FDO66Q) Antibody
Human, Baboon, Primate
ICC, IF, IHC, IHC-Fr, IHC-P
Unconjugated
0.1 ml/$386
HSD3B1 Mouse anti-Human Monoclonal (Biotin) (FDO66Q) Antibody
Bovine, Rat, Baboon, Primate, Human
ICC, IF, IHC, IHC-Fr, IHC-P
Biotin Conjugated
0.1 ml/$416
HSD3B1 Mouse anti-Human Monoclonal (DY488) (FDO66Q) Antibody
Human, Baboon
ICC, IF, IHC, IHC-Fr, IHC-P
DY488 Conjugated
0.1 ml/$416
HSD3B1 Mouse anti-Human Monoclonal (DY650) (FDO66Q) Antibody
Human, Baboon
ICC, IF, IHC, IHC-Fr, IHC-P
DY650 Conjugated
0.1 ml/$416
HSD3B1 Mouse anti-Human Monoclonal (DY550) (FDO66Q) Antibody
Human, Baboon
ICC, IF, IHC, IHC-Fr, IHC-P
DY550 Conjugated
0.1 ml/$416
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$294; 100 µg/$360
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
HSD3B1 Rabbit anti-Human Polyclonal (aa26-55) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
HSD3B1 Rabbit anti-Human Polyclonal (aa26-55) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
HSD3B1 Rabbit anti-Human Polyclonal (aa26-55) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
HSD3B1 Rabbit anti-Human Polyclonal (aa26-55) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
HSD3B1 Rabbit anti-Human Polyclonal (aa26-55) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
HSD3B1 Rabbit anti-Human Polyclonal (aa26-55) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$357
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Human
IP, WB
Unconjugated
100 µl/$749
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$749
HSD3B1 Rabbit anti-Human Polyclonal (APC) Antibody
Human
WB
APC Conjugated
100 µl/$937
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
50 µl/$286; 100 µl/$321
HSD3B1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
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