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Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to heparan sulfate. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes Simplex Virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate.
Gene Name: | heparan sulfate (glucosamine) 3-O-sulfotransferase 6 |
Synonyms: | HS3ST6, 3-OST-6, H3-OST-6 |
Target Sequences: | Q96QI5 Q96QI5 |
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