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HPTPB / PTPRB

protein tyrosine phosphatase, receptor type, B

HPTPB / PTPRB is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene.

Gene Name: protein tyrosine phosphatase, receptor type, B
Family/Subfamily: Protein Phosphatase , R3
Synonyms: PTPRB, HPTPB, PTPB, Ptpbeta, VEPTP, R-PTP-BETA, VE-PTP, HPTP-BETA
Target Sequences: NM_002837 NP_002828.3 P23467

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ELISA Kits (5)
Sandwich (5)
HPTPB / PTPRB (5)
Human (1)
Chicken (1)
Monkey (1)
Porcine (1)
Rabbit (1)
96-Well Strip Plate (5)
No (5)
Plasma (1)
Serum (1)
HPTPB / PTPRB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.31 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
HPTPB / PTPRB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Chicken
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
HPTPB / PTPRB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Monkey
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
HPTPB / PTPRB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Porcine
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
HPTPB / PTPRB ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
125 - 8000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).