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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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HOXD3
homeobox D3
HOXD3 belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes.
| Gene Name: | homeobox D3 |
| Synonyms: | HOXD3, Hox-4.1, HOX1D, HOX4, HOX4A, Homeobox D3, Homeobox protein Hox-4A, Hox-4.1, mouse, homolog of, Homeo box D3, Homeobox protein Hox-D3 |
| Target Sequences: | NM_006898 NP_008829.3 P31249 |
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