HORMAD2

HORMA domain containing 2

Essential for synapsis surveillance during meiotic prophase via the recruitment of ATR activity. Plays a key role in the male mid-pachytene checkpoint and the female meiotic prophase checkpoint: required for efficient build-up of ATR activity on unsynapsed chromosome regions, a process believed to form the basis of meiotic silencing of unsynapsed chromatin (MSUC) and meiotic prophase quality control in both sexes. Required for the DNA double-strand break-independent, BRCA1-dependent activation of ATR on the sex chromosomes that is essential for normal sex body formation.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

HORMAD2 (4)

Publications

No (4)

Tag

GST (1)

Myc-DDK (Flag) (3)

Species

Human (3)

Source

293T Cells (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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HORMAD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G106235

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.1 kDa

Price:

100 µg/$494

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Human HORMAD2 Protein (Recombinant GST) (Full Length) - LS-G36723

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

61.7 kDa

Price:

10 µg/$479; 25 µg/$670

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Human HORMAD2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72933

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.1 kDa

Price:

20 µg/$1,107

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Human HORMAD2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93961

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

35.1 kDa

Price:

20 µg/$150

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