HNRPA1 / HnRNP A1

heterogeneous nuclear ribonucleoprotein A1

HNRPA1 / HnRNP A1 belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites.

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Products

ELISA Kits (8)

Type

Custom (4)

Sandwich (3)

Sandwich CLIA (1)

Target

HNRPA1 / HnRNP A1 (8)

Reactivity

Human (1)

Mouse (4)

Rat (2)

Bovine (1)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (1)

96-Well Strip Plate (5)

Publications

No (8)

Sample Type

Plasma (4)

Serum (4)

Tissue Homogenates (1)

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Mouse HNRPA1 / HnRNP A1 (CLIA) ELISA Kit - LS-F30782

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

15.625 - 1000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$728

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Mouse HNRPA1 / HnRNP A1 (Sandwich ELISA) ELISA Kit - LS-F23714

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

39.063 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse HNRPA1 / HnRNP A1 (Sandwich ELISA) ELISA Kit - LS-F36093

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

39.063 - 2500 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Rat HNRPA1 / HnRNP A1 (Sandwich ELISA) ELISA Kit - LS-F38650

Type:

Sandwich

Format:

12 x 8-Well Microstrips

Reactivity:

Rat

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse HNRPA1 / HnRNP A1 (Custom) ELISA Kit - LS-F65465

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Price:

1 Plate/$783

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Human HNRPA1 / HnRNP A1 (Custom) ELISA Kit - LS-F65579

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Human

Price:

1 Plate/$783

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Bovine HNRPA1 / HnRNP A1 (Custom) ELISA Kit - LS-F65604

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Bovine

Price:

1 Plate/$783

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Rat HNRPA1 / HnRNP A1 (Custom) ELISA Kit - LS-F65753

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Price:

1 Plate/$783

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