HNRNPD / AUF1

heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)

Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Also binds to double- and single-stranded DNA sequences in a specific manner and functions a transcription factor. Each of the RNA-binding domains specifically can bind solely to a single-stranded non-monotonous 5'-UUAG-3' sequence and also weaker to the single-stranded 5'-TTAGGG-3' telomeric DNA repeat. Binds RNA oligonucleotides with 5'-UUAGGG-3' repeats more tightly than the telomeric single-stranded DNA 5'-TTAGGG-3' repeats. Binding of RRM1 to DNA inhibits the formation of DNA quadruplex structure which may play a role in telomere elongation. May be involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. May play a role in the regulation of the rhythmic expression of circadian clock core genes. Directly binds to the 3'UTR of CRY1 mRNA and induces CRY1 rhythmic translation. May also be involved in the regulation of PER2 translation.

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Products

Proteins (15)

Type

Over-Expression Lysate (8)

Recombinant (7)

Target

HNRNPD / AUF1 (15)

Publications

No (15)

Tag

GST (2)

His, N-Terminal (1)

Myc-DDK (Flag) (12)

Species

Human (11)

Source

293T Cells (4)

E. coli (2)

HEK 293 Cells (8)

Wheat Germ Extract (1)

Purification

Purified (1)

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HNRNPD / AUF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122506

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.5 kDa

Price:

100 µg/$494

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HNRNPD / AUF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109240

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.1 kDa

Price:

100 µg/$494

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HNRNPD / AUF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G109241

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

100 µg/$494

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HNRNPD / AUF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G118164

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.7 kDa

Price:

100 µg/$494

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Human HNRNPD / AUF1 Protein (Recombinant His, N-Terminal) - LS-G144076

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

32.7 kDa

Price:

50 µg/$419

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Human HNRNPD / AUF1 Protein (Recombinant GST) (Full Length) - LS-G28875

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

64.8 kDa

Price:

2 µg/$439

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Human HNRNPD / AUF1 Protein (Recombinant GST) (aa18-355) - LS-G22169

Source:

E. coli

Tag:

GST

Molecular Weight:

58.6 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human HNRNPD / AUF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72329

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

20 µg/$1,107

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Human HNRNPD / AUF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72331

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.7 kDa

Price:

20 µg/$1,107

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Human HNRNPD / AUF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72330

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.1 kDa

Price:

20 µg/$1,107

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Human HNRNPD / AUF1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72332

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.5 kDa

Price:

20 µg/$1,107

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Human HNRNPD / AUF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92037

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

32.7 kDa

Price:

20 µg/$150

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Human HNRNPD / AUF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92036

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

30.5 kDa

Price:

20 µg/$150

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Human HNRNPD / AUF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92038

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

36.1 kDa

Price:

20 µg/$150

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Human HNRNPD / AUF1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92040

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

38.3 kDa

Price:

20 µg/$150

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