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HMX3

H6 family homeobox 3

Transcription factor involved in specification of neuronal cell types and which is required for inner ear and hypothalamus development. Binds to the 5'-CAAGTG-3' core sequence. Controls semicircular canal formation in the inner ear. Also required for hypothalamic/pituitary axis of the CNS.

Gene Name:	H6 family homeobox 3
Synonyms:	HMX3, Homeobox protein HMX3, Homeobox protein Nkx-5.1, H6 family homeobox 3, Homeobox (H6 family) 3, NKX5.1, NKX-5.1, Nkx5-1, Homeo box (H6 family) 3
Target Sequences:	EAW49289.1 A6NHT5

Publications (2)

Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia. Stefan Nagel, Claudia Pommerenke, Corinna Meyer, Roderick A F MacLeod, Hans G Drexler. PloS one. 2020 October;15:e0240120. [Full Text Article] [PubMed:33048949] [PMC:PMC7553312] Related Antibodies: LS-B8011.

Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects. Steffes G, Lorente-C[Character e1]novas B, Pearson S, Brooker RH, Spiden S, Kiernan AE, Gu[Character e9]net JL, Steel KP. PloS one. 7:e51065. [Full Text Article] [PubMed:23226461] [PMC:PMC3511360] Related Antibodies: LS-B8011.

HMX3 Protein - Purified recombinant protein HMX3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining

Human HMX3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G72637

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

37.6 kDa

Price:

20 µg/$1,107

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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