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HMX2 is a member of the NKL homeobox family of transcription factors. Members in this family are of ancient origin and play an important role in organ development during embryogenesis. A related mouse protein plays a role in patterning of inner ear structures. In humans, variations in a region containing this gene have been associated with inner ear malformations, vestibular dysfunction, and hearing loss.
Gene Name: | H6 family homeobox 2 |
Synonyms: | HMX2, Homeobox protein HMX2, H6 family homeobox 2, Homeo box (H6 family) 2, Nkx5-2, H6L |
Target Sequences: | NP_005510.1 A2RU54 |
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