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HMG2 / HMGB2

high mobility group box 2

HMG2 / HMGB2 is a member of the non-histone chromosomal high mobility group protein family. The proteins of this family are chromatin-associated and ubiquitously distributed in the nucleus of higher eukaryotic cells. In vitro studies have demonstrated that this protein is able to efficiently bend DNA and form DNA circles. These studies suggest a role in facilitating cooperative interactions between cis-acting proteins by promoting DNA flexibility. This protein was also reported to be involved in the final ligation step in DNA end-joining processes of DNA double-strand breaks repair and V(D)J recombination.

Gene Name: high mobility group box 2
Synonyms: HMGB2, HMG-2, High mobility group box 2, High-mobility group box 2, HMG2, High mobility group protein 2, High mobility group protein B2
Target Sequences: NM_002129 NP_002120.1 P26583

Publications (1)

1
HIV antiretroviral therapy drugs induce premature senescence and altered physiology in HUVECs. Justin Cohen, Luca D'Agostino, Ferit Tuzer, Claudio Torres. Mechanisms of ageing and development. 2018 October;175:74-82. [Full Text Article] [PubMed:30055190] [PMC:PMC6133242] Related Antibodies: LS-B4355.

☰ Filters
Products
Proteins (16)
Over-Expression Lysate (6)
Recombinant (10)
HMG2 / HMGB2 (16)
No (16)
6His, C-terminus (2)
GST (2)
GST, N-terminus (1)
His (2)
His, N-Terminal (1)
His-T7 (1)
Myc-DDK (Flag) (7)
Human (12)
Rat (1)
293T Cells (3)
Baculovirus (1)
E. coli (3)
HEK 293 Cells (4)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (3)
Purified (5)
Low endotoxin level (3)
HMG2 / HMGB2 Protein
Select
Baculovirus
His
100 µg/$411; 500 µg/$985; 20 µg/$276
HMG2 / HMGB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.9 kDa
100 µg/$494
HMG2 / HMGB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
23.9 kDa
100 µg/$494
HMG2 / HMGB2 Protein - Recombinant High Mobility Group Box Protein 2 (HMGB2) by SDS-PAGE
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E. coli
His, N-Terminal
29kDa
10 µg/$268; 50 µg/$362; 200 µg/$722; 100 µg/$577; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
HMG2 / HMGB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
23.9 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.1 kDa
10 µg/$317; 50 µg/$524
HMG2 / HMGB2 Protein - 12.5% SDS-PAGE of human HMGB2 stained with Coomassie Blue
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Wheat Germ Extract
GST
47.19 kDa
10 µg/$479; 25 µg/$670
HMG2 / HMGB2 Protein - 12.5% SDS-PAGE of human HMGB2 stained with Coomassie Blue
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Wheat Germ Extract
GST
50.4 kDa
10 µg/$479; 25 µg/$670
HMG2 / HMGB2 Protein - Recombinant  High Mobility Group Box Protein 2 By SDS-PAGE
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E. coli
His-T7
24.7 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
HMG2 / HMGB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.9 kDa
20 µg/$150
Select
293T Cells
Myc-DDK (Flag)
23.9 kDa
20 µg/$150
HMG2 / HMGB2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
23.9 kDa
20 µg/$150
HMG2 / HMGB2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HMG2 / HMGB2 Protein - Purified recombinant protein HMGB2 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
23.9 kDa
20 µg/$1,107
Select
E. coli
113 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
12.54 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.07kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Viewing 1-16 of 16 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).