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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

Research Areas
Cell Cycle Pathways
Protein Family And Group
Infectious Disease
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HM13 / IMP-1 / SPP

histocompatibility (minor) 13

Catalyzes intramembrane proteolysis of some signal peptides after they have been cleaved from a preprotein, resulting in the release of the fragment from the ER membrane into the cytoplasm. Required to generate lymphocyte cell surface (HLA-E) epitopes derived from MHC class I signal peptides. May play a role in graft rejection (By similarity). May be necessary for the removal of the signal peptide that remains attached to the hepatitis C virus core protein after the initial proteolytic processing of the polyprotein. Involved in the intramembrane cleavage of the integral membrane protein PSEN1.

Gene Name: histocompatibility (minor) 13
Family/Subfamily: Protease , Aspartic A22B
Synonyms: HM13, DJ324O17.1, HIMP1, IMP1, Intramembrane protease 1, H13, MSTP086, IMP-1, IMPAS, IMPAS-1, Presenilin-like protein 3, PSL3, Signal peptide peptidase, Signal peptide peptidase beta, SPP, PSENL3, SPPL1
Target Sequences: NM_030789 NP_110416.1 Q8TCT9


☰ Filters
HM13 / IMP-1 / SPP Antibody - Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE), at a concentration of 10 ug/ml.
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $425.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Mouse, Human
ELISA, WB
HRP Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Mouse, Human
ELISA, WB
Biotin Conjugated
50µg   $285.00; 100µg   $385.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Mouse, Human
ELISA, WB
FITC Conjugated
50µg   $285.00; 100µg   $385.00
HM13 / IMP-1 / SPP Antibody - HM13 antibody Western blot of Mouse Spleen lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse HM13 / IMP-1 / SPP
Xenopus, Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Human
WB
Unconjugated
100µl   0.5mg/ml   $365.00
HM13 / IMP-1 / SPP Antibody - HM13 antibody Western blot of Mouse Spleen lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse HM13 / IMP-1 / SPP
Xenopus, Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Gibbon, Human
WB
HRP Conjugated
100µl   0.65mg/ml   $385.00
HM13 / IMP-1 / SPP Antibody - HM13 antibody Western blot of Mouse Spleen lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse HM13 / IMP-1 / SPP
Xenopus, Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Gibbon, Human
WB
Biotin Conjugated
100µl   1mg/ml   $385.00
HM13 / IMP-1 / SPP Antibody - HM13 antibody Western blot of Mouse Spleen lysate. Antibody concentration 1 ug/ml. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
Rabbit Polyclonal to Mouse HM13 / IMP-1 / SPP
Xenopus, Chicken, Bovine, Rabbit, Mouse, Rat, Pig, Gibbon, Human
WB
FITC Conjugated
100µl   1mg/ml   $385.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
ELISA, IHC, WB
Unconjugated
100µg   $355.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
ELISA, WB
Unconjugated
200µl   $590.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
ELISA, WB
Biotin Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
ELISA, WB
FITC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
ELISA, WB
APC Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
ELISA, WB
AP Conjugated
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
ELISA, WB
HRP Conjugated, Azide-free
200µl   $740.00
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
ELISA, WB
PE Conjugated
200µl   $740.00
HM13 / IMP-1 / SPP Antibody - Detection of Human SPP by Western Blot. Samples: Whole cell lysate (50 ug) prepared using NETN buffer from HeLa, 293T, and Jurkat cells. Antibodies: Affinity purified rabbit anti-SPP antibody used for WB at 0.1 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
Rabbit Polyclonal (IgG) to Human HM13 / IMP-1 / SPP
Human
IP, WB
Unconjugated
100µl   1mg/ml   $405.00
HM13 / IMP-1 / SPP Antibody - HM13 Antibody western blot of HeLa cell line lysates (35 ug/lane). The HM13 antibody detected the HM13 protein (arrow).
Select
Rabbit Polyclonal to Human HM13 / IMP-1 / SPP
Human
WB
Unconjugated
400µl   $325.00
Viewing 1-18 of 18 products



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).