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Post-translational modification of specific protein by attachment of biotin. Acts on various carboxylases such as acetyl-CoA-carboxylase, pyruvate carboxylase, propionyl CoA carboxylase, and 3-methylcrotonyl CoA carboxylase.
Gene Name: | holocarboxylase synthetase (biotin-(proprionyl-CoA-carboxylase (ATP-hydrolysing)) ligase) |
Synonyms: | HLCS, Biotin--protein ligase, HCS, Biotin apo-protein ligase |
Target Sequences: | NM_000411 NP_000402.3 P50747 |
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