HLA-DPA1

major histocompatibility complex, class II, DP alpha 1

HLA-DPA1 belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DPA) and a beta (DPB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DP molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to 4 different molecules.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

HLA-DPA1 (4)

Publications

No (4)

Tag

6His, N-terminus (1)

GST (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human HLA-DPA1 Protein (Recombinant 6His, N-terminus) (aa29-222) - LS-G22648

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

26.4 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human HLA-DPA1 Protein (Recombinant GST) (Full Length) - LS-G28836

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

54.34 kDa

Price:

2 µg/$439

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Human HLA-DPA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76536

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.1 kDa

Price:

20 µg/$150

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HLA-DPA1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G102137

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

26.1 kDa

Price:

100 µg/$494

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