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HEY1

hes-related family bHLH transcription factor with YRPW motif 1

Downstream effector of Notch signaling which may be required for cardiovascular development. Transcriptional repressor which binds preferentially to the canonical E box sequence 5'-CACGTG-3'. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6.

Gene Name: hes-related family bHLH transcription factor with YRPW motif 1
Synonyms: HEY1, BHLHb31, CHF2, CHF-2, HERP2, HRT1, HESR-1, HHRT1, HRT-1, OAF1, HESR1
Target Sequences: NM_012258 NP_036390.3 Q9Y5J3

Publications (1)

1
Hypoxia regulates the mitochondrial activity of hepatocellular carcinoma cells through HIF/HEY1/PINK1 pathway. Kung-Chun Chiu D, Pui-Wah Tse A, Law CT, Ming-Jing Xu I, Lee D, Chen M, Kit-Ho Lai R, Wai-Hin Yuen V, Wing-Sum Cheu J, Wai-Hung Ho D, Wong CM, Zhang H, Oi-Lin Ng I, Chak-Lui Wong C. Cell death & disease. 2019 December;10:934. [Full Text Article] [PubMed:31819034] [PMC:PMC6901483]

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Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
HEY1 (8)
No (8)
GST (1)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
Myc-DDK (Flag) (5)
Human (6)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (2)
Purified (1)
HEY1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32.9 kDa
20 µg/$150
HEY1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
32.4 kDa
20 µg/$150
HEY1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
32.4 kDa
100 µg/$494
HEY1 Protein
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E. coli
GST, N-terminus + His, C-terminus
58.4 kDa
50 µg/$419
HEY1 Protein - 12.5% SDS-PAGE of human HEY1 stained with Coomassie Blue
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Wheat Germ Extract
GST
59.07 kDa
10 µg/$479; 25 µg/$670
HEY1 Protein - Purified recombinant protein HEY1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
32.9 kDa
20 µg/$1,107
HEY1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEY1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
32.9 kDa
100 µg/$494
Viewing 1-8 of 8 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).