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HDAC7

histone deacetylase 7

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.

Gene Name: histone deacetylase 7
Family/Subfamily: Histone Deacetylase , not assigned-Histone Deacetylase
Synonyms: HDAC7, DKFZP586J0917, HD7, Histone deacetylase 7, Histone deacetylase 7A, HD7A, HDAC7A
Target Sequences: NM_016596

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Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
HDAC7 (7)
No (7)
GST (1)
His (2)
Myc-DDK (Flag) (4)
Human (6)
293T Cells (1)
E. coli (2)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Purified (1)
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E. coli
His
26.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HDAC7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
99.5 kDa
20 µg/$215
HDAC7 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
99.5 kDa
100 µg/$710
HDAC7 Protein
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E. coli
His
33.1 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
HDAC7 Protein - 12.5% SDS-PAGE of human HDAC7A stained with Coomassie Blue
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Wheat Germ Extract
GST
56.1 kDa
10 µg/$479; 25 µg/$670
HDAC7 Protein - Purified recombinant protein HDAC7 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
106.6 kDa
20 µg/$1,107
HDAC7 Protein - Purified recombinant protein HDAC7A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
99.5 kDa
20 µg/$1,107
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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).