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Unfortunately, the antibody (ID:50553) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



HDAC2

histone deacetylase 2

Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, CAF1. Deacetylates TSHZ3 and regulates its transcriptional repressor activity. Component of a RCOR/GFI/KDM1A/HDAC complex that suppresses, via histone deacetylase (HDAC) recruitment, a number of genes implicated in multilineage blood cell development. May be involved in the transcriptional repression of circadian target genes, such as PER1, mediated by CRY1 through histone deacetylation. Involved in MTA1-mediated transcriptional corepression of TFF1 and CDKN1A.

Gene Name: histone deacetylase 2
Family/Subfamily: Histone Deacetylase , not assigned-Histone Deacetylase
Synonyms: HDAC2, HD2, Histone deacetylase 2, RPD3, YAF1, YY1-associated factor 1
Target Sequences: NM_001527 NP_001518.3

Publications (1)

1
Epigenetic modifications induced by RGC-32 in colon cancer. Vlaicu SI, Tegla CA, Cudrici CD, Fosbrink M, Nguyen V, Azimzadeh P, Rus V, Chen H, Mircea PA, Shamsuddin A, Rus H. Experimental and molecular pathology. 2010 88:67-76. (WB) [PubMed:19883641] [PMC:PMC2815209]

Filtered By: None
Target
hdac2 (85)
Reactivity
Human (85)
Mouse (57)
Rat (39)
Bat (2)
Bovine (23)
Chicken (19)
Chimpanzee (10)
Dog (2)
Gibbon (10)
Guinea pig (11)
Hamster (8)
Horse (11)
Monkey (20)
Non-Human Primate (1)
Orangutan (1)
Pig (15)
Primate (2)
Rabbit (5)
Sheep (2)
Xenopus (1)
Application
IHC (40)
IHC-P (19)
WB (79)
Flo (10)
ChrIP (2)
ELISA (26)
ICC (15)
IF (23)
IP (22)
Peptide-ELISA (4)
Host
rabbit (75)
mouse (9)
goat (1)
Isotype
IgG (41)
IgG1 (9)
Clonality
monoclonal mc (9)
polyclonal pc (76)
Clone
1194CT18.5.1 (1)
13A192 (1)
4C10C3 (1)
Format
AP Conjugated (4)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (7)
FITC Conjugated (7)
HRP Conjugated (7)
Magnetic beads Conjugated (1)
PE Conjugated (4)
Sepharose Conjugated (1)
Unconjugated (50)
Epitope
C-Terminus (19)
pSer394 (10)
aa410-439 (8)
aa419-468 (4)
aa464-478 (4)
N-Terminus (2)
Asp388 (1)
aa202-488 (1)
aa330-410 (1)
aa360-409 (1)
aa462-478 (1)
internal region (1)
Publications
No (85)
Showing 1-25 out of 85 results
HDAC2 Antibody (N-Terminus) IHC-plus™ LS-B3907
Anti-HDAC2 antibody IHC of human colon. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3907 concentration 20 ug/ml.
Anti-HDAC2 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3907 concentration 20 ug/ml.

Rabbit Polyclonal (IgG) to Mouse HDAC2
Mouse, Human
IHC IHC-P WB
Unconjugated
HDAC2 Antibody (aa464-478, Magnetic beads) LS-C172205
 This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HDAC2
Mouse, Rat, Human
IP
Magnetic beads Conjugated
HDAC2 Antibody (aa419-468) IHC-plus™ LS-B965
Anti-HDAC2 antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B965 concentration 5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Jurkat Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HDAC2
Chicken, Bovine, Rabbit, Mouse, Pig, Human, Monkey
IHC IHC-P WB
Unconjugated
HDAC2 Antibody LS-C355664
IHC using HDAC2 Antibody
IF using HDAC2 Antibody

Rabbit Polyclonal (IgG) to Human HDAC2
Mouse, Rat, Hamster, Chimpanzee, Human, Monkey
ChrIP ICC IF IHC IP WB
Unconjugated
HDAC2 Antibody (C-Terminus) LS-C336189
Immunohistochemistry of HDAC2 in rat testis tissue with HDAC2 antibody at 5 ug/mL.
Immunohistochemistry of HDAC2 in rat testis tissue with HDAC2 antibody at 5 µg/mL.

Rabbit Polyclonal (IgG) to Human HDAC2
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated
HDAC2 Antibody (aa410-439) LS-C166821
HDAC2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human lung carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
Fluorescent confocal image of HeLa cell stained with HDAC2 Antibody. HeLa cells were fixed with 4% PFA (20 min), permeabilized with Triton X-100 (0.1%, 10 min), then incubated with HDAC2 primary antibody (1:25, 1 h at 37°C). For secondary antibody, Alexa Fluor 488 conjugated donkey anti-rabbit antibody (green) was used (1:400, 50 min at 37°C). Cytoplasmic actin was counterstained with Alexa Fluor 555 (red) conjugated Phalloidin (7units/ml, 1 h at 37°C). Nuclei were counterstained with DAPI (blue) (10 ug/ml, 10 min). HDAC2 immunoreactivity is localized to Nucleus significantly.

Rabbit Polyclonal to Human HDAC2
Human
Flo IF IHC IHC-P WB
Unconjugated
HDAC2 Antibody (aa410-439) LS-C321903

Rabbit Polyclonal (IgG) to Human HDAC2
Human
ELISA Flo IF IHC WB
Unconjugated
HDAC2 Antibody (aa410-439, Biotin) LS-C258347

Rabbit Polyclonal (IgG) to Human HDAC2
Human
ELISA Flo ICC IF IHC WB
Biotin Conjugated
HDAC2 Antibody (aa410-439, FITC) LS-C258348

Rabbit Polyclonal (IgG) to Human HDAC2
Human
ELISA Flo ICC IF IHC WB
FITC Conjugated
HDAC2 Antibody (aa410-439, Azide-free, HRP) LS-C258349

Rabbit Polyclonal (IgG) to Human HDAC2
Human
ELISA Flo ICC IF IHC WB
HRP Conjugated, Azide-free
HDAC2 Antibody (aa410-439, AP) LS-C258345

Rabbit Polyclonal (IgG) to Human HDAC2
Human
ELISA Flo ICC IF IHC WB
AP Conjugated
HDAC2 Antibody (aa410-439, APC) LS-C258346

Rabbit Polyclonal (IgG) to Human HDAC2
Human
ELISA Flo ICC IF IHC WB
APC Conjugated
HDAC2 Antibody (aa410-439, PE) LS-C258354

Rabbit Polyclonal (IgG) to Human HDAC2
Human
ELISA Flo ICC IF IHC WB
PE Conjugated
HDAC2 Antibody (aa360-409) IHC-plus™ LS-B6853
Anti-HDAC2 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B6853 dilution 1:200.
Western blot of extracts from HepG2 cells, using HDAC2 (Ab-394) Antibody. The lane on the right is treated with the synthesized peptide.

Rabbit Polyclonal (IgG) to Human HDAC2
Mouse, Rat, Human
IHC IHC-P Peptide-ELISA WB
Unconjugated
HDAC2 Antibody LS-C666098

Rabbit Polyclonal (IgG) to Human HDAC2
Human
ELISA Flo IF IHC IP WB
Unconjugated
HDAC2 Antibody LS-C331881
Immunohistochemistry of paraffin-embedded rat kidney tissue.
Immunohistochemistry of paraffin-embedded human lung cancer tissue.

Rabbit Polyclonal (IgG) to Human HDAC2
Mouse, Rat, Human
IF IHC IP WB
Unconjugated
HDAC2 Antibody (C-Terminus) IHC-plus™ LS-B13664
Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Testis: Formalin-Fixed, Paraffin-Embedded (FFPE)

Rabbit Polyclonal to Human HDAC2
Human
ELISA IHC IHC-P WB
Unconjugated
HDAC2 Antibody (phospho-Ser394) LS-C203029
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using Rabbit Anti-HDAC2 (Phospho-Ser394) Polyclonal Antibody.
Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear staining using. Rabbit Anti-HDAC2 (Phospho-Ser394) Polyclonal Antibody.

Rabbit Polyclonal to Human HDAC2
Mouse, Rat, Human
IF IHC IHC-P WB
Unconjugated
HDAC2 Antibody (phospho-Ser394) LS-C205264
Immunohistochemistry of paraffin-embedded human breast carcinoma tissue using HDAC2 (Phospho-Ser394) antibody (left) or the same antibody preincubated with blocking peptide (right).
Immunofluorescence of methanol-fixed HeLa cells showing nuclear staining using HDAC2 (Phospho-Ser394) antibody.

Rabbit Polyclonal to Human HDAC2
Mouse, Rat, Human
IF IHC IHC-P WB
Unconjugated
HDAC2 Antibody (C-Terminus) LS-C36601

Rabbit Polyclonal to Human HDAC2
Mouse, Rat, Human, Monkey
ELISA ICC IF WB
Unconjugated
HDAC2 Antibody (C-Terminus) LS-C209351
Western Blot of Rabbit Anti-HDAC2 antibody. Lane 1: mouse brain extract. Lane 2: mouse brain extract blocked with peptide. Load: 4 ug per lane. Primary antibody: HDAC2 antibody at 1ug/mL for overnight at 4 degrees C. Secondary antibody: IRDye800 alpha rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4 degrees C. Predicted/Observed size: 59 kDa for HDAC2.

Rabbit Polyclonal to Human HDAC2
Mouse, Rat, Primate, Human
ELISA IF IHC WB
Unconjugated
HDAC2 Antibody (C-Terminus) LS-C209355
Western Blot of Rabbit anti-HDAC2 antibody. Lane 1: mouse brain extract. Lane 2: mouse brain extract blocked with peptide. Load: 4 ug per lane. Primary antibody: HDAC2 antibody at 1ug/mL for overnight at 4 degrees C. Secondary antibody: IRDye800 alpha rabbit secondary antibody at 1:10,000 for 45 min at RT. Block: 5% BLOTTO overnight at 4 degrees C. Predicted/Observed size: 59 kDa for HDAC2. Other band(s): ~45kDa.

Rabbit Polyclonal to Human HDAC2
Mouse, Rat, Primate, Human
ELISA IF IHC WB
Unconjugated
HDAC2 Antibody (C-Terminus) IHC-plus™ LS-B8044
Anti-HDAC2 antibody IHC of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B8044 dilution 5-7.5 ug/ml.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
HDAC2 antibody LS-B8044 Western blot of HT1080 cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

Rabbit Polyclonal to Human HDAC2
Chicken, Bovine, Mouse, Guinea pig, Rat, Pig, Horse, Human, Monkey
IHC IHC-P WB
Unconjugated
HDAC2 Antibody (internal region) LS-C742395
Antibody Immunofluorescence analysis of paraformaldehyde fixed U251 cells, permeabilized with 0.15% Triton. Primary incubation 1hr (10ug/ml) followed by Alexa Fluor 488 secondary antibody (2ug/ml), showing nuclear staining. The nuclear stain is DAPI (blue)
Antibody (1µg/ml) staining of HEK293 nuclear cell lysate. (35µg protein in RIPA buffer). Detected by chemiluminescence.

Goat Polyclonal to Human HDAC2
Human
Flo IF Peptide-ELISA WB
Unconjugated
HDAC2 Antibody (C-Terminus) LS-C287573
Detection of Human HDAC2 by Immunohistochemistry. Sample: FFPE section of human ovarian carcinoma. Antibody: Affinity purified rabbit anti-HDAC2 used at a dilution of 1:200 (1 Detection: DAB.

Rabbit Polyclonal (IgG) to Human HDAC2
Mouse, Human
ChrIP IF IHC IHC-P IP WB
Unconjugated

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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