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HCFC2
host cell factor C2
HCFC2 encodes one of two proteins which interact with VP16, a herpes simplex virus protein that initiates virus infection. Both the encoded protein and the original Herpes host cell factor interact with VP16 through a beta-propeller domain. The original Herpes host cell factor, however, is effective at initiating viral infection while the encoded protein is not. Transcripts of varying length due to alternative polyadenylation signals have been described.
| Gene Name: | host cell factor C2 |
| Synonyms: | HCFC2, Host cell factor 2, Host cell factor C2, HCF-2, HCF2, C2 factor |
| Target Sequences: | NM_013320 NP_037452.1 Q9Y5Z7 |
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