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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565
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Additional Contact Details
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HBP17 / FGFBP1
fibroblast growth factor binding protein 1
HBP17 / FGFBP1 is a secreted fibroblast growth factor carrier protein. The encoded protein plays a critical role in cell proliferation, differentiation and migration by binding to fibroblast growth factors and potentiating their biological effects on target cells. The encoded protein may also play a role in tumor growth as an angiogenic switch molecule, and expression of this gene has been associated with several types of cancer including pancreatic and colorectal adenocarcinoma. A pseudogene of this gene is also located on the short arm of chromosome 4.
| Gene Name: | fibroblast growth factor binding protein 1 |
| Synonyms: | FGFBP1, 17 kDa HBGF-binding protein, FGF-BP, HBP17, FGF-binding protein 1, FGFBP-1, FGF-BP1, FGFBP |
| Target Sequences: | NM_005130 NP_005121.1 Q14512 |
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