HAT1

histone acetyltransferase 1

Histone acetylation, particularly of histone H4, has been proposed to play an important role in replication-dependent nucleosome assembly. The HAT1 protein contains D, A, and B motifs, which are present in many N-acetyltransferases, including those that acetylate substrates other than histones. The HAT1 holoenzyme consists of 2 subunits: the catalytic 46-kD HAT1 and the accessory p46. The p46 subunit stimulated the activity of HAT1 and bound to core histones. The HAT1 holoenzyme acetylated newly synthesized but not nucleosomal histone H4 at lys5 and lys12, and, to a lesser extent, histone H2A at lys5. HAT1 and p46 polypeptides are located in the nucleus of S-phase cells.

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Proteins (6)

Type

Over-Expression Lysate (2)

Recombinant (4)

Target

HAT1 (6)

Publications

No (6)

Tag

GST (1)

GST, N-terminus (1)

His (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Mouse (1)

Source

293T Cells (1)

E. coli (2)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (2)

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HAT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120908

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.6 kDa

Price:

100 µg/$494

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Human HAT1 Protein (Recombinant GST) (Full Length) - LS-G31187

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

62.48 kDa

Price:

10 µg/$479; 25 µg/$670

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Human HAT1 Protein (Recombinant GST, N-terminus) (aa310-419) - LS-G60760

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human HAT1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80419

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

39.6 kDa

Price:

20 µg/$150

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Human HAT1 Protein (Recombinant His) - LS-G732

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276; 20 µg/$332; 100 µg/$544; 500 µg/$1,473

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Mouse HAT1 Protein (Recombinant His-T7) (aa100-338) - LS-G14501

Source:

E. coli

Tag:

His-T7

Molecular Weight:

32.0 kDa

Price:

10 µg/$277; 50 µg/$420; 100 µg/$670; 200 µg/$837; 1 mg/$1,928; 500 µg/$1,474; 5 mg/$2,927; 2 mg/$2,113

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