Hairless / HR

hair growth associated

Hairless / HR is a protein that is involved in hair growth. This protein functions as a transcriptional corepressor of multiple nuclear receptors, including thyroid hormone receptor, the retinoic acid receptor-related orphan receptors and the vitamin D receptors, and it interacts with histone deacetylases. The translation of this protein is modulated by a regulatory open reading frame (ORF) that exists upstream of the primary ORF. Mutations in this upstream ORF cause Marie Unna hereditary hypotrichosis (MUHH), an autosomal dominant form of genetic hair loss. Mutations in this gene also cause autosomal recessive congenital alopecia and atrichia with papular lesions, other diseases resulting in hair loss. Two transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (7)

Type

Over-Expression Lysate (4)

Recombinant (3)

Target

Hairless / HR (7)

Publications

No (7)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (6)

Species

Human (5)

Source

293T Cells (2)

HEK 293 Cells (4)

Wheat Germ Extract (1)

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Hairless / HR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G111745

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121.7 kDa

Price:

100 µg/$710

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Human Hairless / HR Protein (Recombinant GST, N-terminus) (aa1090-1189) - LS-G62757

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Hairless / HR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G116149

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

127.3 kDa

Price:

100 µg/$494

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Human Hairless / HR Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67713

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

127.3 kDa

Price:

20 µg/$1,107

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Human Hairless / HR Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67714

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121.7 kDa

Price:

20 µg/$1,107

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Human Hairless / HR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80556

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

127.3 kDa

Price:

20 µg/$150

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Human Hairless / HR Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G80557

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

121.7 kDa

Price:

20 µg/$215

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