HACE1

HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1

E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regulation of small GTPases. Acts as a regulator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regulates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regulator via its interaction with RARB.

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Products

Antibodies (42)

Type

Primary (42)

Target

HACE1 (42)

Reactivity

Human (42)

Mouse (13)

Rat (10)

Bovine (3)

Chimpanzee (6)

Dog (3)

Gibbon (6)

Guinea pig (6)

Horse (3)

Monkey (6)

Orangutan (3)

Pig (3)

Rabbit (6)

Xenopus (4)

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Application

IHC (8)

IHC-P (4)

WB (30)

ELISA (16)

IF (5)

Peptide-ELISA (1)

Host

rabbit (20)

mouse (22)

Isotype

IgG (14)

IgG,k (3)

IgG1 (6)

IgG1,k (1)

IgG2a,k (6)

IgG2b (4)

IgG2c (2)

Clonality

monoclonal mc (22)

polyclonal pc (20)

Clone

1854CT757.66.47 (1)

8D3 (3)

OTI10D3 (2)

OTI2C7 (2)

OTI3F5 (2)

OTI4E10 (2)

OTI4F10 (2)

OTI6H8 (2)

Format

APC Conjugated (1)

Biotin Conjugated (5)

Carrier-free (6)

FITC Conjugated (5)

HRP Conjugated (4)

PE Conjugated (1)

Unconjugated (26)

Epitope

N-Terminus (4)

aa792-841 (4)

Internal (1)

aa800-900 (1)

Publications

No (42)

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HACE1 Antibody (clone 8D3, FITC) LS-C347809

Antibody:

HACE1 Mouse anti-Human Monoclonal (FITC) (8D3) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

FITC Conjugated

Price:

100 µg/$409

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HACE1 Antibody (clone 8D3, Biotin) LS-C347808

Antibody:

HACE1 Mouse anti-Human Monoclonal (Biotin) (8D3) Antibody

Reactivity:

Human

Applications:

ELISA, IF, IHC, IHC-P, WB

Format:

Biotin Conjugated

Price:

100 µg/$396

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HACE1 Antibody LS-C666064

Antibody:

HACE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$351

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HACE1 Antibody (Internal) LS-C153439

Antibody:

HACE1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Xenopus, Mouse, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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HACE1 Antibody LS-C673029

Antibody:

HACE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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HACE1 Antibody LS-C807942

Antibody:

HACE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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HACE1 Antibody LS-C411127

Antibody:

HACE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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HACE1 Antibody LS-C403200

Antibody:

HACE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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HACE1 Antibody LS-C406440

Antibody:

HACE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC

Format:

Unconjugated

Price:

20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450

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HACE1 Antibody (clone 1854CT757.66.47) LS-C757871

Antibody:

HACE1 Mouse anti-Human Monoclonal (1854CT757.66.47) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$393

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HACE1 Antibody LS-C780177

Antibody:

HACE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

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HACE1 Antibody (clone OTI4E10) LS-C795247

Antibody:

HACE1 Mouse anti-Human Monoclonal (OTI4E10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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HACE1 Antibody (clone OTI4E10, Carrier-free) LS-C799676

Antibody:

HACE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4E10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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HACE1 Antibody (clone OTI6H8) LS-C795257

Antibody:

HACE1 Mouse anti-Human Monoclonal (OTI6H8) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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HACE1 Antibody (clone OTI6H8, Carrier-free) LS-C792338

Antibody:

HACE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI6H8) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

HACE1 Antibody (aa800-900) LS-C308172

Antibody:

HACE1 Mouse anti-Human Monoclonal (aa800-900) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

100 µg/$705

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HACE1 Antibody (clone OTI10D3) LS-C795280

Antibody:

HACE1 Mouse anti-Human Monoclonal (OTI10D3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

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HACE1 Antibody (clone OTI10D3, Carrier-free) LS-C792352

Antibody:

HACE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI10D3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

HACE1 Antibody (clone OTI3F5) LS-C795250

Antibody:

HACE1 Mouse anti-Human Monoclonal (OTI3F5) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

HACE1 Antibody (clone OTI3F5, Carrier-free) LS-C792331

Antibody:

HACE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI3F5) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

HACE1 Antibody (clone OTI4F10) LS-C795251

Antibody:

HACE1 Mouse anti-Human Monoclonal (OTI4F10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

HACE1 Antibody (clone OTI4F10, Carrier-free) LS-C792335

Antibody:

HACE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI4F10) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

HACE1 Antibody (clone OTI2C7) LS-C795254

Antibody:

HACE1 Mouse anti-Human Monoclonal (OTI2C7) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$434

Select

HACE1 Antibody (clone OTI2C7, Carrier-free) LS-C792332

Antibody:

HACE1 Mouse anti-Human Monoclonal (Carrier-free) (OTI2C7) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

Select

HACE1 Antibody LS-C767083

Antibody:

HACE1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Viewing 26-42 of 42 product results

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