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GZMH / Granzyme H

granzyme H (cathepsin G-like 2, protein h-CCPX)

GZMH / Granzyme H is a member of the granzyme family. Members of this family are highly conserved serine proteases that eliminate transformed cells and virus-infected cells. This protein, which has chymotrypsin-like activity, has a preference for bulky aromatic amino acids at the P1 position and for acidic residues at the P3' and P4' positions. This protein is reported to be constitutively expressed in NK cells and may play a role in the cytotoxic arm of the innate immune response by inducing target cell death and by directly cleaving substrates in pathogen-infected cells. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

Gene Name: granzyme H (cathepsin G-like 2, protein h-CCPX)
Family/Subfamily: Protease , Serine S1
Synonyms: GZMH, CCP-X, CGL-2, CGL2, CTSGL2, Cathepsin G-like 2, CTLA1, Cytotoxic serine protease C, Cytotoxin serine protease-C, Granzyme H, H-CCPX, CSP-C
Target Sequences: NM_033423 NP_219491.1 P20718

☰ Filters
Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
GZMH / Granzyme H (8)
No (8)
GST (1)
GST, N-terminus (2)
His (2)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (7)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Human Cells (1)
Wheat Germ Extract (3)
Purified (3)
Low endotoxin level (1)
GZMH / Granzyme H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
27.1 kDa
100 µg/$494
GZMH / Granzyme H Protein - 12.5% SDS-PAGE of human GZMH stained with Coomassie Blue
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Wheat Germ Extract
GST
53.7 kDa
10 µg/$479; 25 µg/$670
GZMH / Granzyme H Protein - Recombinant  Granzyme H By SDS-PAGE
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E. coli
His-T7
29.1 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
GZMH / Granzyme H Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
27.1 kDa
20 µg/$150
GZMH / Granzyme H Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GZMH / Granzyme H Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GZMH / Granzyme H Protein
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E. coli
His
20 µg/$361; 100 µg/$739; 4 µg/$261
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Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
26.7 kDa
50 µg/$854
Viewing 1-8 of 8 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).