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Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Several transcript variants encoding a few different isoforms have been found for this gene.
Gene Name: | guanylate cyclase 1, soluble, alpha 3 |
Family/Subfamily: | Guanyl cyclase , not assigned-Guanyl cyclase |
Synonyms: | GUCY1A3, GC-S-alpha-1, GUC1A3, GUCA3, GCS-alpha-3, GUCY1A1, GC-SA3, GCS-alpha-1, GUCSA3 |
Target Sequences: | NM_000856 NP_000847.2 Q02108 |
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