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GUCA2B / Uroguanylin

guanylate cyclase activator 2B (uroguanylin)

Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins. May be a potent physiological regulator of intestinal fluid and electrolyte transport. May be an autocrine/paracrine regulator of intestinal salt and water transport.

Gene Name: guanylate cyclase activator 2B (uroguanylin)
Synonyms: GUCA2B, Guanylate cyclase activator 2B, UGN, Uroguanylin, GCAP-II
Target Sequences: NM_007102 NP_009033.1 Q16661

Publications (1)

1
UEG Week 2019 Oral Presentations. No authors listed. United European gastroenterology journal. 2019 October;7:10-188. [Full Text Article] [PubMed:32213000] Related Antibodies: LS-C371347.

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).