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GUCA2A / Guanylin

guanylate cyclase activator 2A (guanylin)

Endogenous activator of intestinal guanylate cyclase. It stimulates this enzyme through the same receptor binding region as the heat-stable enterotoxins.

Gene Name: guanylate cyclase activator 2A (guanylin)
Synonyms: GUCA2A, GCAP-I, Guanylate cyclase activator 2A, Guanylin, GUCA2, STARA
Target Sequences: M97496 AAA35915.1 Q02747

Publications (2)

1
Obesity-Induced Colorectal Cancer Is Driven by Caloric Silencing of the Guanylin-GUCY2C Paracrine Signaling Axis. Lin JE, Colon-Gonzalez F, Blomain E, Kim GW, Aing A, Stoecker B, Rock J, Snook AE, Zhan T, Hyslop TM, Tomczak M, Blumberg RS, Waldman SA. Cancer research. 2016 76:339-46. (WB, ELISA; Mouse, Human) [Full Text Article] [PubMed:26773096] [PMC:PMC4717834] Related Antibodies: LS-C166741.
2
Immunohistochemical Staining for Uroguanylin, a Satiety Hormone, is Decreased in Intestinal Tissue Specimens From Female Adolescents With Obesity. Di Guglielmo MD, Perdue L, Adeyemi A, van Golen KL, Corao DU. Pediatric and developmental pathology : the official journal of the Society for Pediatric Pathology and the Paediatric Pathology Society. 2018 May;21:285-295. [Full Text Article] [PubMed:28847213] [PMC:PMC5647253] Related Antibodies: LS-B9726.

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Products
Proteins (4)
Over-Expression Lysate (2)
Recombinant (2)
GUCA2A / Guanylin (4)
No (4)
GST (1)
Myc-DDK (Flag) (3)
Human (3)
293T Cells (1)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
GUCA2A / Guanylin Protein - Purified recombinant protein GUCA2A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
12.2 kDa
20 µg/$1,107
GUCA2A / Guanylin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
12.2 kDa
100 µg/$494
GUCA2A / Guanylin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
12.2 kDa
20 µg/$150
GUCA2A / Guanylin Protein - 12.5% SDS-PAGE of human GUCA2A stained with Coomassie Blue
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Wheat Germ Extract
GST
38.8 kDa
10 µg/$479; 25 µg/$670
Viewing 1-4 of 4 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).