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Required for RNA polymerase III-mediated transcription. Component of TFIIIC that initiates transcription complex assembly on tRNA and is required for transcription of 5S rRNA and other stable nuclear and cytoplasmic RNAs. Binds to the box B promoter element.
Gene Name: | general transcription factor IIIC, polypeptide 1, alpha 220kDa |
Synonyms: | GTF3C1, TF3C-alpha, TFIIIC 220 kDa subunit, TFIIIC box B-binding subunit, TFIIICalpha, TFIIIC220, TFIIIC |
Target Sequences: | NM_001520 NP_001511.2 Q12789 |
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