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GSTM1

glutathione S-transferase mu 1

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu gene have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens. Multiple protein isoforms are encoded by transcript variants of this gene.

Gene Name: glutathione S-transferase mu 1
Synonyms: GSTM1, Glutathione S-aryltransferase, GSTM1-1, GSTM1a-1a, GSTM1b-1b, Glutathione S-alkyltransferase, GTH4, GST class-mu 1, GST1, GTM1, H-B, HB subunit 4, MU-1, Glutathione S-transferase M1, Glutathione S-transferase mu 1, GST HB subunit 4
Target Sequences: NM_000561 NP_000552.2 P09488

Publications (2)

1
5,6-Dihydrocyclopenta[c][1,2]-dithiole-3(4H)-thione is a promising cancer chemopreventive agent in the urinary bladder. Paonessa JD, Munday CM, Mhawech-Fauceglia P, Munday R, Zhang Y. Chemico-biological interactions. 2009 180:119-26. (IHC-P; Rat) [Full Text Article] [PubMed:19121294] [PMC:PMC2684030] Related Antibodies: LS-B963.
2
Multimeric structures of HLA-G isoforms function through differential binding to LILRB receptors. Sirinyan M, Sennlaub F, Dorfman A, Sapieha P, Gobeil F, Hardy P, Lachapelle P, Chemtob S. Cellular and molecular life sciences : CMLS. 2012 (Flo; Human) [PubMed:22802125]

☰ Filters
Products
Proteins (19)
Over-Expression Lysate (5)
Recombinant (14)
GSTM1 (19)
No (19)
GST (2)
GST, N-terminus (1)
GST, N-terminus + His, C-terminus (1)
His (5)
His, N-Terminal (3)
His, N-terminus (1)
Myc-DDK (Flag) (5)
Chicken (1)
Human (10)
Mouse (4)
Rat (2)
293T Cells (3)
E. coli (11)
HEK 293 Cells (2)
Wheat Germ Extract (3)
Purified (3)
Low endotoxin level (1)
Biologically active (2)
GSTM1 Protein - Recombinant Glutathione S Transferase Mu 1 By SDS-PAGE
Select
E. coli
His, N-Terminal
27.1 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
GSTM1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
25.5 kDa
100 µg/$494
GSTM1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
21.1 kDa
100 µg/$494
Select
293T Cells
Myc-DDK (Flag)
25.5 kDa
20 µg/$150
GSTM1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
25.5 kDa
20 µg/$150
GSTM1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
21.1 kDa
20 µg/$150
GSTM1 Protein - Recombinant Mouse GSTM1 Protein (His Tag)-Elabscience
Select
E. coli
His, N-terminus
25.7 kDa
20 µg/$270; 100 µg/$390
GSTM1 Protein
Select
E. coli
GST, N-terminus + His, C-terminus
49.1 kDa
50 µg/$419
GSTM1 Protein
Select
E. coli
His, N-Terminal
21.1 kDa
50 µg/$419
GSTM1 Protein - 12.5% SDS-PAGE of human GSTM1 stained with Coomassie Blue
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Wheat Germ Extract
GST
45.65 kDa
2 µg/$439
GSTM1 Protein - 12.5% SDS-PAGE of human GSTM1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
47.7 kDa
2 µg/$439
GSTM1 Protein
Select
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
GSTM1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
GSTM1 Protein
Select
E. coli
None
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
100 µg/$317; 500 µg/$526; 20 µg/$245
GSTM1 Protein
Select
E. coli
His
Biologically active
100 µg/$342; 500 µg/$641; 20 µg/$254
GSTM1 Protein - Active Glutathione S Transferase Mu 1 (GSTm1) by WB
Select
E. coli
His, N-Terminal
27kDa
10 µg/$377; 50 µg/$942; 200 µg/$1,600; 100 µg/$1,367; 1 mg/$3,009; 500 µg/$2,423; 5 mg/$6,581; 2 mg/$3,511
Select
E. coli
His
27.2 kDa
10 µg/$252; 50 µg/$315; 100 µg/$417; 200 µg/$522; 1 mg/$1,404; 500 µg/$1,034; 5 mg/$2,303; 2 mg/$1,565
GSTM1 Protein - Recombinant Glutathione S Transferase Mu 1 By SDS-PAGE
Select
E. coli
His
27.0 kDa
10 µg/$277; 50 µg/$415; 100 µg/$662; 200 µg/$830; 1 mg/$1,916; 500 µg/$1,465; 5 mg/$2,899; 2 mg/$2,101
Select
E. coli
His
27.2 kDa
10 µg/$255; 50 µg/$323; 100 µg/$450; 200 µg/$562; 1 mg/$1,480; 500 µg/$1,096; 5 mg/$2,395; 2 mg/$1,646
Viewing 1-19 of 19 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).