GSTA2

glutathione S-transferase alpha 2

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

GSTA2 (8)

Publications

No (8)

Tag

GST (1)

GST, N-terminus (2)

His (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (2)

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Mouse GSTA2 Protein (Recombinant His-T7) (aa1-222) - LS-G24569

Source:

E. coli

Tag:

His-T7

Molecular Weight:

29.1 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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GSTA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122959

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.5 kDa

Price:

100 µg/$494

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Human GSTA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88718

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.5 kDa

Price:

20 µg/$150

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Human GSTA2 Protein (Recombinant GST) (Full Length) - LS-G28736

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

52.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human GSTA2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71090

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

25.5 kDa

Price:

20 µg/$1,107

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Human GSTA2 Protein (Recombinant GST, N-terminus) (aa1-222) - LS-G56308

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human GSTA2 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G58776

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GSTA2 Protein (Recombinant His) (aa1-222) - LS-G14506

Source:

E. coli

Tag:

His

Molecular Weight:

26.9 kDa

Price:

10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060

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