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GRPR

gastrin-releasing peptide receptor

Gastrin-releasing peptide (GRP) regulates numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation and is a potent mitogen for neoplastic tissues. The effects of GRP are mediated through the gastrin-releasing peptide receptor. This receptor is a glycosylated, 7-transmembrane G-protein coupled receptor that activates the phospholipase C signaling pathway. The receptor is aberrantly expressed in numerous cancers such as those of the lung, colon, and prostate. An individual with autism and multiple exostoses was found to have a balanced translocation between chromosome 8 and a chromosome X breakpoint located within the gastrin-releasing peptide receptor gene.

Gene Name: gastrin-releasing peptide receptor
Family/Subfamily: GPCR , Bombesin
Synonyms: GRPR, GRP-R, Bombesin BB2 receptor, GRP receptor, Grp/bombesin receptor
Target Sequences: NM_005314 NP_005305.1 P30550

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
GRPR (5)
No (5)
GST (1)
His-GST (1)
His-T7 (1)
Myc-DDK (Flag) (2)
Human (3)
Mouse (1)
293T Cells (1)
E. coli (2)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
GRPR Protein - Recombinant Gastrin Releasing Peptide Receptor By SDS-PAGE
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E. coli
His-GST
42.8 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
GRPR Protein - 12.5% SDS-PAGE of human GRPR stained with Coomassie Blue
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Wheat Germ Extract
GST
69.6 kDa
2 µg/$439
GRPR Protein - Recombinant  Gastrin Releasing Peptide Receptor By SDS-PAGE
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E. coli
His-T7
16.3 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
GRPR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
43 kDa
20 µg/$150
GRPR Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
43 kDa
100 µg/$494
Viewing 1-5 of 5 product results


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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).