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GRM5 / MGLUR5

glutamate receptor, metabotropic 5

Group I of the Metabotropic Glutamate Receptors includes GRM1 and GRM5, receptors that have been shown to activate phospholipase C. Alternative splice variants of GRM5 have been described, but their full-length nature has not been determined. Inflammation results in the activation of mGluR1 and mGluR5 in dorsal horn neurons of the spinal cord, leading to extracellular signal-regulated kinase (ERK) activation, which is required for nociceptive plasticity and enhanced pain. GRM5 is involved in inflammatory mechanical hyperalgesia and potentially in schizophrenia. Summary of expresson: GRM5 has been reported to be expressed in various regions of the brain as well as in the spinal cord and dorsal root ganglia.

Gene Name: glutamate receptor, metabotropic 5
Family/Subfamily: GPCR , Metabotropic glutamate
Synonyms: GRM5, GPRC1E, MGLUR5, Mglur5b, MGlu5
Target Sequences: NM_000842 NP_000833.1 P41594

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ELISA Kits (4)
Sandwich (4)
GRM5 / MGLUR5 (4)
Human (1)
Mouse (2)
Rat (1)
96-Well Strip Plate (4)
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Plasma (4)
Serum (4)
Tissue Homogenates (1)
GRM5 / MGLUR5 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GRM5 / MGLUR5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GRM5 / MGLUR5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GRM5 / MGLUR5 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
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Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).