GRIN2B / NMDAR2B / NR2B

glutamate receptor, ionotropic, N-methyl D-aspartate 2B

N-methyl-D-aspartate (NMDA) receptors are a class of ionotropic glutamate receptors. NMDA receptor channel has been shown to be involved in long-term potentiation, an activity-dependent increase in the efficiency of synaptic transmission thought to underlie certain kinds of memory and learning. NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D). GRIN2B may be a candidate gene for the neurodegenerative disorder dentato-rubro-pallidoluysian atrophy (DRPLA). Overexpression of the NR2B subunit of the receptor has been associated with increases in learning and memory while aged; memory impaired animals have deficiencies in NR2B expression. Tyr1472 on NR2B is phosphorylated and this may lead to the increased expression of the NMDAR at the synapse that plays a role in synaptic plasticity.

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Products

ELISA Kits (8)

Type

Cell-Based (1)

Cell-Based Phosphorylation (3)

Sandwich (4)

Target

GRIN2B / NMDAR2B / NR2B (8)

Reactivity

Human (7)

Mouse (5)

Rat (4)

Format

96-Well Microplate (5)

96-Well Strip Plate (3)

Publications

No (8)

Sample Type

Adherent Cell Cultures (4)

Cell Lysates (1)

Plasma (3)

Serum (3)

Tissue Homogenates (3)

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Mouse/Human/Rat GRIN2B / NMDAR2B / NR2B (Cell-Based ELISA) ELISA Kit - LS-F2189

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$618

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Human GRIN2B / NMDAR2B / NR2B (Sandwich ELISA) ELISA Kit - LS-F22095

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.31 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$651

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Mouse GRIN2B / NMDAR2B / NR2B (Sandwich ELISA) ELISA Kit - LS-F50972

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$958

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Mouse/Human/Rat Phospho-GRIN2B / NMDAR2B / NR2B (Tyr1336) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1717

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Mouse/Human/Rat Phospho-GRIN2B / NMDAR2B / NR2B (Tyr1474) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1194

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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Human GRIN2B / NMDAR2B / NR2B (Sandwich ELISA) ELISA Kit - LS-F33640

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

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Human GRIN2B / NMDAR2B / NR2B (Sandwich ELISA) ELISA Kit - LS-F8965

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Tissue Homogenates

Price:

1 Plate/$834

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Mouse/Human/Rat Phospho-GRIN2B / NMDAR2B / NR2B (Ser1303) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1755

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$668

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