GRID2

glutamate receptor, ionotropic, delta 2

GRID2 is a member of the family of ionotropic glutamate receptors which are the predominant excitatory neurotransmitter receptors in the mammalian brain. The encoded protein is a multi-pass membrane protein that is expressed selectively in cerebellar Purkinje cells. A point mutation in the mouse ortholog, associated with the phenotype named 'lurcher', in the heterozygous state leads to ataxia resulting from selective, cell-autonomous apoptosis of cerebellar Purkinje cells during postnatal development. Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis. This protein also plays a role in synapse organization between parallel fibers and Purkinje cells. Alternate splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause cerebellar ataxia in humans.

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Products

Antibodies (7)

Type

Primary (7)

Target

GRID2 (7)

Reactivity

Human (7)

Mouse (6)

Rat (6)

Zebrafish (1)

Application

WB (7)

ELISA (3)

ICC (1)

IF (6)

Peptide-ELISA (2)

Host

rabbit (6)

mouse (1)

Isotype

IgG (4)

IgG1,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (6)

Clone

1A1 (1)

Format

Unconjugated (7)

Epitope

800-880 aa, C-terminal (1)

C-Terminus (1)

Gly860 (1)

aa831-880 (1)

Publications

No (7)

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GRID2 Antibody (C-Terminus) LS-C356070

Antibody:

GRID2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Zebrafish, Rat, Mouse, Human

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$299

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GRID2 Antibody (aa831-880) LS-C119523

Antibody:

GRID2 Rabbit anti-Human Polyclonal (aa831-880) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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GRID2 Antibody (Gly860) LS-C177347

Antibody:

GRID2 Rabbit anti-Human Polyclonal (Gly860) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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GRID2 Antibody (800-880 aa, C-terminal) LS-C383703

Antibody:

GRID2 Rabbit anti-Human Polyclonal (800-880 aa, C-terminal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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GRID2 Antibody LS-C823552

Antibody:

GRID2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

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GRID2 Antibody LS-C804690

Antibody:

GRID2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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GRID2 Antibody (clone 1A1) LS-C197352

Antibody:

GRID2 Mouse anti-Human Monoclonal (1A1) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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