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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GREM2 / Gremlin 2

gremlin 2, DAN family BMP antagonist

GREM2 / Gremlin 2 is a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

Gene Name: gremlin 2, DAN family BMP antagonist
Synonyms: GREM2, CKTSF1B2, DAN domain family member 3, DAND3, Gremlin-2, Gremlin 2, PRDC
Target Sequences: NM_022469 NP_071914.3 Q9H772

Filtered By: None
Target
GREM2 / Gremlin 2 (30)
Reactivity
Human (30)
Mouse (10)
Rat (5)
Chicken (4)
Chimpanzee (3)
Guinea pig (4)
Monkey (4)
Application
IHC (12)
IHC-P (2)
WB (20)
ELISA (10)
ICC (2)
IP (1)
Host
rabbit (22)
mouse (8)
Isotype
IgG (16)
IgG2a,k (7)
Clonality
monoclonal mc (7)
polyclonal pc (23)
Format
AP Conjugated (1)
APC (1)
APC Conjugated (2)
Biotin Conjugated (4)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (12)
Epitope
aa22-168 (10)
N-Terminus (4)
Internal (1)
Publications
No (30)
Showing 1-25 of 30 results

GREM2 / Gremlin 2 Antibody IHC-plus™ LS-B8919
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Mouse, Rat, Human
ELISA IHC IHC-P
Unconjugated
50µl 0.97mg/ml  $425.00
Anti-GREM2 / Gremlin 2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GREM2 / Gremlin 2 antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GREM2 / Gremlin 2 Antibody LS-C147150
Rabbit Polyclonal to Human GREM2 / Gremlin 2
Mouse, Rat, Human
WB
Unconjugated
30µg  $245.00; 100µg 0.5mg/ml  $405.00

GREM2 / Gremlin 2 Antibody (N-Terminus) LS-C116717
Rabbit Polyclonal to Human GREM2 / Gremlin 2
Chicken, Mouse, Guinea pig, Human, Monkey
WB
Unconjugated
50µg  $365.00
GREM2 / Gremlin 2 antibody LS-C116717 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
GREM2 / Gremlin 2 antibody LS-C116717 Western blot of 721_B cell lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

GREM2 / Gremlin 2 Antibody LS-C743248
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Mouse, Human
ELISA IHC WB
Unconjugated
50µg 1mg/ml  $265.00; 100µg 1mg/ml  $325.00

GREM2 / Gremlin 2 Antibody LS-C754248
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
ELISA IHC
Unconjugated
100µg  $355.00

GREM2 / Gremlin 2 Antibody LS-C311195
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC IHC-P IP
Unconjugated
100µl  $605.00
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

GREM2 / Gremlin 2 Antibody (aa22-168) LS-C375012
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $315.00; 1ml 0.5mg/ml  $575.00; 10ml 0.5mg/ml  $2,295.00
Western blot of GREM2 / Gremlin 2 antibody.
Western blot of GREM2 / Gremlin 2 antibody.

GREM2 / Gremlin 2 Antibody (aa22-168, HRP) LS-C714675
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $355.00; 1ml  $740.00; 10ml  $2,985.00
Western blot of GREM2 / Gremlin 2 antibody.
Western blot of GREM2 / Gremlin 2 antibody.

GREM2 / Gremlin 2 Antibody (aa22-168, Biotin) LS-C425254
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $395.00

GREM2 / Gremlin 2 Antibody (aa22-168, Biotin) LS-C689546
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC WB
Biotin Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of GREM2 / Gremlin 2 antibody.
Western blot of GREM2 / Gremlin 2 antibody.

GREM2 / Gremlin 2 Antibody (aa22-168, FITC) LS-C425253
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $415.00

GREM2 / Gremlin 2 Antibody (aa22-168, FITC) LS-C696672
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC WB
FITC Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $345.00; 1ml  $695.00; 10ml  $2,760.00
Western blot of GREM2 / Gremlin 2 antibody.
Western blot of GREM2 / Gremlin 2 antibody.

GREM2 / Gremlin 2 Antibody (aa22-168, APC) LS-C719776
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $325.00; 200µl  $395.00; 1ml  $860.00; 10ml  $7,125.00
Western blot of GREM2 / Gremlin 2 antibody.
Western blot of GREM2 / Gremlin 2 antibody.

GREM2 / Gremlin 2 Antibody (aa22-168, Cy3) LS-C705658
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC WB
Cy3 Conjugated
20µl  $255.00; 100µl  $375.00; 200µl  $465.00; 1ml  $1,140.00; 10ml  $4,605.00
Western blot of GREM2 / Gremlin 2 antibody.
Western blot of GREM2 / Gremlin 2 antibody.

GREM2 / Gremlin 2 Antibody (aa22-168, PE) LS-C728744
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $345.00; 1ml  $695.00; 10ml  $2,760.00
Western blot of GREM2 / Gremlin 2 antibody.
Western blot of GREM2 / Gremlin 2 antibody.

GREM2 / Gremlin 2 Antibody (aa22-168, APC, Cy7) LS-C737593
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Human
IHC WB
APC, Cy7 Conjugated
20µl  $295.00; 100µl  $485.00; 200µl  $695.00; 1ml  $1,725.00; 10ml  $6,900.00
Western blot of GREM2 / Gremlin 2 antibody.
Western blot of GREM2 / Gremlin 2 antibody.

GREM2 / Gremlin 2 Antibody LS-C308112
Mouse Monoclonal (IgG2a,k) to Human GREM2 / Gremlin 2
Human
ELISA
Unconjugated
100µg  $560.00

GREM2 / Gremlin 2 Antibody (HRP) LS-C542401
Mouse Monoclonal (IgG2a,k) to Human GREM2 / Gremlin 2
Human
ELISA
HRP Conjugated
100µl  $710.00

GREM2 / Gremlin 2 Antibody (Biotin) LS-C522268
Mouse Monoclonal (IgG2a,k) to Human GREM2 / Gremlin 2
Human
ELISA
Biotin Conjugated
100µl  $710.00

GREM2 / Gremlin 2 Antibody (FITC) LS-C532313
Mouse Monoclonal (IgG2a,k) to Human GREM2 / Gremlin 2
Human
ELISA
FITC Conjugated
100µl  $710.00

GREM2 / Gremlin 2 Antibody (AP) LS-C504343
Mouse Monoclonal (IgG2a,k) to Human GREM2 / Gremlin 2
Human
ELISA
AP Conjugated
100µl  $710.00

GREM2 / Gremlin 2 Antibody (APC) LS-C514053
Mouse Monoclonal (IgG2a,k) to Human GREM2 / Gremlin 2
Human
ELISA
APC Conjugated
100µl  $710.00

GREM2 / Gremlin 2 Antibody (Internal) LS-C356069
Rabbit Polyclonal to Human GREM2 / Gremlin 2
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $245.00
Western blot analysis of Gremlin 2 expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.
Western blot analysis of Gremlin 2 expression in HEK293T (A); Raw264.7 (B); H9C2 (C) whole cell lysates.

GREM2 / Gremlin 2 Antibody LS-C412029
Rabbit Polyclonal to Human GREM2 / Gremlin 2
Mouse, Rat, Human
WB
Unconjugated
100µl 1mg/ml  $385.00
Western blot of GREM2 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: H9C2 whole cell lysate.
Western blot of GREM2 antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: Raw264.7 whole cell lysate. Lane 3: H9C2 whole cell lysate.

GREM2 / Gremlin 2 Antibody LS-C749293
Rabbit Polyclonal (IgG) to Human GREM2 / Gremlin 2
Mouse, Rat, Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of mouse brain, using GREM2 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Western blot analysis of extracts of mouse brain, using GREM2 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Showing 1-25 of 30 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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