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GPX6 / GPX-6 product belongs to the glutathione peroxidase family, which functions in the detoxification of hydrogen peroxide. It contains a selenocysteine (Sec) residue at its active site. The selenocysteine is encoded by the UGA codon, which normally signals translation termination. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Expression of this gene is restricted to embryos and adult olfactory epithelium.
Gene Name: | glutathione peroxidase 6 (olfactory) |
Synonyms: | GPX6, DJ1186N24, DJ1186N24.1, GPx-6, GPX5p, GSHPx-6, Glutathione peroxidase 6, GPXP3 |
Target Sequences: | NP_874360.1 P59796 |
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