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2 Shaker Rd Suites
B001/B101
Shirley, MA 01464
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Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036
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GPRC6A
G protein-coupled receptor, class C, group 6, member A
Receptor activated by amino acids with a preference for basic amino acids such as L-Lys, L-Arg and L-ornithine but also by small and polar amino acids. The L-alpha amino acids respond is augmented by divalent cations Ca2+ and Mg2+. Activated by extracellular calcium and osteocalin. Seems to act through a G(q)/G(11) and G(i)-coupled pathway. Mediates the non-genomic effects of androgens in multiple tissue. May coordinates nutritional and hormonal anabolic signals through the sensing of extracellular amino acids, osteocalcin, divalents ions and its responsiveness to anabolic steroids.
| Gene Name: | G protein-coupled receptor, class C, group 6, member A |
| Family/Subfamily: | GPCR , Amino Acid Receptor |
| Synonyms: | GPRC6A, BA86F4.3, HGPCR33, HGPRC6A, Predicted with SOSUI analysis |
| Target Sequences: | NM_148963 NP_683766.2 Q5T6X5 |
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