GPNMB / Osteoactivin

glycoprotein (transmembrane) nmb

GPNMB / Osteoactivin is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (16)

Type

Over-Expression Lysate (2)

Recombinant (14)

Target

GPNMB / Osteoactivin (16)

Application

SDS-PAGE (3)

Publications

No (16)

Tag

6His, C-terminus (2)

Fc, C-terminus (1)

GST (1)

GST, N-terminus (1)

His (5)

His,C-terminus (2)

Human IgG Fc, C-terminus (1)

Myc-DDK (Flag) (3)

Species

Human (12)

Mouse (3)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (6)

Human Cells (3)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (10)

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Mouse GPNMB / Osteoactivin Protein (Recombinant His,C-terminus) (Met1-Asn502) - LS-G49248

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant mouse GPNMB comprises 490 amino acids and has a predicted molecular mass of 54.9 kDa. The apparent molecular mass of the protein is approximately 96 kDa in SDS-PAGE under reducing conditions due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

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Human GPNMB / Osteoactivin Protein (Recombinant His) - LS-G2501

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Human GPNMB / Osteoactivin Protein (Recombinant 6His, C-terminus) (Ala22-Pro486) - LS-G39002

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

53.09kD

Price:

10 µg/$269; 50 µg/$372; 500 µg/$1,585; 1 mg/$2,157

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Human GPNMB / Osteoactivin Protein (Recombinant GST, N-terminus) (aa104-203) - LS-G61515

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GPNMB / Osteoactivin Protein (Recombinant Human IgG Fc, C-terminus) (Met1-Pro474) - LS-G141222

Source:

HEK 293 Cells

Tag:

Human IgG Fc, C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human GPNMB/Fc is a disulfide-linked homodimer. The reduced monomer comprises 694 amino acids and has a predicted molecular mass of 77.8 kDa. The apparent molecular mass of the protein is approximately 114 kDa in SDS-PAGE under reducing conditions.

Price:

100 µg/$441

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Human GPNMB / Osteoactivin Protein (Recombinant GST) (Full Length) - LS-G32162

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

88.44 kDa

Price:

2 µg/$439

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Human GPNMB / Osteoactivin Protein (Recombinant His,C-terminus) (Met1-Pro474) - LS-G48626

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human GPNMB consists of 464 amino acids and predictes a molecular mass of 52.1 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhGPNMB is approximately 85-90 kDa due to glycosylation.

Price:

100 µg/$441; 1 mg/$2,003

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Human GPNMB / Osteoactivin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66780

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

61.5 kDa

Price:

20 µg/$1,107

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Mouse GPNMB / Osteoactivin Protein (Recombinant His) (Met1-Asn502) - LS-G98168

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

54.9 kDa

Price:

100 µg/$721

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Human GPNMB / Osteoactivin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78489

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.92 kDa

Price:

20 µg/$150

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GPNMB / Osteoactivin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99264

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63.92 kDa

Price:

100 µg/$494

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Human GPNMB / Osteoactivin Protein (Recombinant His) (Met1-Pro474) - LS-G97519

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

52.1 kDa

Price:

100 µg/$721

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Human GPNMB / Osteoactivin Protein (Recombinant His) (aa322-486) - LS-G140953

Source:

E. coli

Sequence Length:

164 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

18.15 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

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Mouse GPNMB / Osteoactivin Protein (Recombinant His) (aa67-166) - LS-G140958

Source:

E. coli

Sequence Length:

99 AA

Tag:

His

Endotoxin Level:

Less than 0.1 EU/µg protein (determined by LAL method).

Molecular Weight:

11 kDa

Price:

10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531

Select

Human GPNMB / Osteoactivin Protein (Recombinant 6His, C-terminus) (Ala22-Pro486) - LS-G138928

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

53.1 kDa

Price:

10 µg/$269; 50 µg/$367

Select

Human GPNMB / Osteoactivin Protein (Recombinant Fc, C-terminus) (Met1-Pro474) - LS-G138032

Source:

HEK 293 Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

77.8 kDa

Price:

100 µg/$721

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