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GPN1 / XAB1
GPN-loop GTPase 1
Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII) (PubMed:20855544, PubMed:21768307). May act at an RNAP assembly step prior to nuclear import (PubMed:21768307). Forms an interface between the RNA polymerase II enzyme and chaperone/scaffolding proteins, suggesting that it is required to connect RNA polymerase II to regulators of protein complex formation (PubMed:17643375). May be involved in nuclear localization of XPA (PubMed:11058119).
| Gene Name: | GPN-loop GTPase 1 |
| Family/Subfamily: | Ras GTPase superfamily IPR001806 , not assigned-Ras GTPase superfamily IPR001806 |
| Synonyms: | GPN1, ATP(GTP)-binding protein, ATPBD1A, GPN-loop GTPase 1, MBD2-interacting protein, RPAP4, XPA binding protein 1, GTPase, MBDIN, NTPBP, XAB1, XPA binding protein 1, XPA-binding protein 1 |
| Target Sequences: | NM_007266 NP_009197.2 Q9HCN4 |
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