GPI

glucose-6-phosphate isomerase

GPI is a member of the glucose phosphate isomerase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. In the cytoplasm, the gene product functions as a glycolytic enzyme (glucose-6-phosphate isomerase) that interconverts glucose-6-phophsate and fructose-6-phosphate. Extracellularly, the encoded protein (also referred to as neuroleukin) functions as a neurotrophic factor that promotes survival of skeletal motor neurons and sensory neurons, and as a lymphokine that induces immunoglobulin secretion. The encoded protein is also referred to as autocrine motility factor based on an additional function as a tumor-secreted cytokine and angiogenic factor. Defects in this gene are the cause of nonspherocytic hemolytic anemia and a severe enzyme deficiency can be associated with hydrops fetalis, immediate neonatal death and neurological impairment. Alternative splicing results in multiple transcript variants.

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Products

Proteins (16)

Type

Over-Expression Cell Culture Supernatant (1)

Over-Expression Lysate (5)

Recombinant (10)

Target

GPI (16)

Publications

No (16)

Tag

6His-B2M, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (3)

His, N-Terminal (2)

His-T7 (3)

Myc-DDK (Flag) (5)

Species

Human (10)

Mouse (3)

Rat (1)

Source

293T Cells (2)

E. coli (6)

HEK 293 Cells (5)

Wheat Germ Extract (2)

Yeast (1)

Purification

Purified (2)

Low Endotoxin Level

Low endotoxin level (1)

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Mouse GPI Protein (Recombinant His) (Full Length) - LS-G22941

Source:

Yeast

Tag:

His

Molecular Weight:

64.6 kD

Price:

100 µg/$499; 20 µg/$364; 1 mg/$1,683

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Human GPI Protein (Over-Expression Cell Culture Supernatant His, N-Terminal) (Ala2-Gln558) - LS-G136066

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~63 kDa

Price:

200 µl/$283

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Human GPI Protein (Over-Expression Lysate His, N-Terminal) (Ala2-Gln558) - LS-G136067

Source:

HEK 293 Cells

Tag:

His, N-Terminal

Molecular Weight:

~63 kDa

Price:

100 µg/$298

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GPI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G130027

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.8 kDa

Price:

100 µg/$494

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Human GPI Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G58727

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human GPI Protein (Recombinant GST) (Full Length) - LS-G28684

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

86.9 kDa

Price:

10 µg/$479; 25 µg/$670

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Human GPI Protein (Recombinant His) (Full Length) - LS-G22052

Source:

E. coli

Tag:

His

Molecular Weight:

66.6 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human GPI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76158

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

64.8 kDa

Price:

20 µg/$150

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Human GPI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76156

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63 kDa

Price:

20 µg/$150

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Mouse GPI Protein (Recombinant 6His-B2M, N-terminus) (aa2-558) - LS-G56301

Source:

E. coli

Tag:

6His-B2M, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human GPI Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G65724

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63 kDa

Price:

20 µg/$1,107

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GPI Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98952

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

63 kDa

Price:

100 µg/$494

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Human GPI Protein (Recombinant His) - LS-G572

Source:

E. coli

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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Mouse GPI Protein (Recombinant His-T7) (aa308-558) - LS-G12703

Source:

E. coli

Tag:

His-T7

Molecular Weight:

31.6 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$722; 200 µg/$902; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204

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Human GPI Protein (Recombinant His-T7) (aa263-475) - LS-G12704

Source:

E. coli

Tag:

His-T7

Molecular Weight:

28.1 kDa

Price:

10 µg/$273; 50 µg/$390; 100 µg/$622; 200 µg/$777; 1 mg/$1,840; 500 µg/$1,398; 5 mg/$2,801; 2 mg/$2,023

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Rat GPI Protein (Recombinant His-T7) (aa335-558) - LS-G12705

Source:

E. coli

Tag:

His-T7

Molecular Weight:

25.4 kDa

Price:

10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284

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