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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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GMDS / GMD

GDP-mannose 4,6-dehydratase

GDP-mannose 4,6-dehydratase (GMD; EC 4.2.1.47) catalyzes the conversion of GDP-mannose to GDP-4-keto-6-deoxymannose, the first step in the synthesis of GDP-fucose from GDP-mannose, using NADP+ as a cofactor. The second and third steps of the pathway are catalyzed by a single enzyme, GDP-keto-6-deoxymannose 3,5-epimerase, 4-reductase, designated FX in humans (MIM 137020).

Gene Name: GDP-mannose 4,6-dehydratase
Synonyms: GMDS, GDP-D-mannose dehydratase, GDP-mannose 4,6 dehydratase, GDP-mannose 4,6-dehydratase, GMD, SDR3E1
Target Sequences: NP_001491.1 O60547

Filtered By: None
Target
GMDS / GMD (19)
Reactivity
Human (19)
Mouse (11)
Rat (4)
Bat (4)
Bovine (4)
Chicken (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Hamster (4)
Horse (4)
Monkey (4)
Orangutan (3)
Rabbit (4)
Application
IHC (4)
IHC-P (3)
WB (15)
ELISA (2)
IF (1)
Host
rabbit (18)
mouse (1)
Isotype
IgG (13)
IgG2a (1)
Clonality
monoclonal mc (1)
polyclonal pc (18)
Clone
2A1 (1)
Format
AP Conjugated (1)
APC Conjugated (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (7)
Epitope
aa268-317 (4)
aa67-357 (1)
Publications
No (19)
Showing 1-19 of 19 results

GMDS / GMD Antibody (clone 2A1) IHC-plus™ LS-B12961
Mouse Monoclonal [clone 2A1] (IgG2a) to Human GMDS / GMD
Human
IHC IHC-P WB
Unconjugated
50µl 0.64mg/ml  $425.00
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GMDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GMDS.
Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GMDS (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GMDS.

GMDS / GMD Antibody (aa268-317) LS-C151631
Rabbit Polyclonal to Human GMDS / GMD
Chicken, Bovine, Rat, Hamster, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
WB
Unconjugated
50µg  $365.00
GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

GMDS / GMD Antibody (aa268-317, HRP) LS-C471743
Rabbit Polyclonal to Human GMDS / GMD
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100µl 0.65mg/ml  $385.00
GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

GMDS / GMD Antibody (aa268-317, Biotin) LS-C471740
Rabbit Polyclonal to Human GMDS / GMD
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100µl 1mg/ml  $385.00
GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

GMDS / GMD Antibody (aa268-317, FITC) LS-C471741
Rabbit Polyclonal to Human GMDS / GMD
Chicken, Bovine, Rabbit, Mouse, Dog, Rat, Hamster, Horse, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100µl 1mg/ml  $385.00
GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
GMDS / GMD antibody Western Blot of Human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

GMDS / GMD Antibody LS-C671389
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Human
ELISA IF IHC IHC-P
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of Hela cells at a dilution of 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .
Immunohistochemistry image at a dilution of 1:400 and staining in paraffin-embedded human breast cancer performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Immunofluorescence staining of Hela cells at a dilution of 1:133, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4 °C.The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG (H+L) .

GMDS / GMD Antibody (HRP) LS-C671388
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Human
HRP Conjugated
50µg  $285.00; 100µg  $385.00

GMDS / GMD Antibody (Biotin) LS-C671390
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Human
Biotin Conjugated
50µg  $285.00; 100µg  $385.00

GMDS / GMD Antibody (FITC) LS-C671387
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Human
FITC Conjugated
50µg  $285.00; 100µg  $385.00

GMDS / GMD Antibody LS-C665891
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Human
ELISA IHC WB
Unconjugated
100µg  $335.00

GMDS / GMD Antibody (aa67-357) LS-C186260
Rabbit Polyclonal to Human GMDS / GMD
Human
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $335.00
IHC of paraffin-embedded DLD1 xenograft using GMDS antibody at 1:500 dilution.
Sample (30 ug of whole cell lysate). A: A431 , B: H1299. 10% SDS PAGE. GMDS / GMD antibody diluted at 1:1000.
IHC of paraffin-embedded DLD1 xenograft using GMDS antibody at 1:500 dilution.
Sample (30 ug of whole cell lysate). A: A431 , B: H1299. 10% SDS PAGE. GMDS / GMD antibody diluted at 1:1000.

GMDS / GMD Antibody LS-C310505
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Mouse, Human
WB
Unconjugated
100µg  $605.00

GMDS / GMD Antibody (HRP) LS-C542356
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Mouse, Human
WB
HRP Conjugated
100µl  $755.00

GMDS / GMD Antibody (Biotin) LS-C522225
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Mouse, Human
WB
Biotin Conjugated
100µl  $755.00

GMDS / GMD Antibody (FITC) LS-C532269
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Mouse, Human
WB
FITC Conjugated
100µl  $755.00

GMDS / GMD Antibody (PE) LS-C650470
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Mouse, Human
WB
PE Conjugated
100µl  $755.00

GMDS / GMD Antibody (APC) LS-C514010
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Mouse, Human
WB
APC Conjugated
100µl  $755.00

GMDS / GMD Antibody (AP) LS-C504303
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Mouse, Human
WB
AP Conjugated
100µl  $755.00

GMDS / GMD Antibody LS-C750033
Rabbit Polyclonal (IgG) to Human GMDS / GMD
Human
WB
Unconjugated
50µl  $235.00
Western blot analysis of extracts of HeLa cells, using GMDS antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Western blot analysis of extracts of HeLa cells, using GMDS antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 60s.
Showing 1-19 of 19 results

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PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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