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GLUD1/Glutamate Dehydrogenase

glutamate dehydrogenase 1

GLUD1/Glutamate Dehydrogenase is glutamate dehydrogenase protein; a mitochondrial matrix enzyme that catalyzes the oxidative deamination of glutamate to alpha-ketoglutarate and ammonia. This enzyme has an important role in regulating amino acid induced insulin secretion and activating mutations in this gene are a common cause of congenital hyperinsulinism. This enzyme is allosterically activated by ADP and inhibited by GTP and ATP. The related glutamate dehydrogenase 2 gene on the human X-chromosome originated from this gene via retrotransposition and encodes a soluble form of glutamate dehydrogenase. Multiple pseudogenes of this gene are present in humans.

Gene Name: glutamate dehydrogenase 1
Synonyms: GLUD1, GDH1, GDH 1, Glutamate dehydrogenase 1, Glutamate dehydrogenase 2, GDH, GLUD
Target Sequences: NM_005271 NP_005262.1 P00367

Publications (1)

1
Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. Bao X, Pal R, Hascup KN, Wang Y, Wang WT, Xu W, Hui D, Agbas A, Wang X, Michaelis ML, Choi IY, Belousov AB, Gerhardt GA, Michaelis EK. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2009 29:13929-44. [PubMed:19890003] [PMC:PMC2811066]

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ELISA Kits (27)
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GLUD1/Glutamate Dehydrogenase (27)
Human (7)
Mouse (6)
Rat (5)
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Guinea pig (1)
Monkey (1)
Pig (1)
Porcine (1)
Rabbit (1)
12 x 8-Well Microstrips (2)
96-Well Microplate (2)
96-Well Strip Plate (23)
No (27)
Cell Supernatant (1)
Plasma (17)
Serum (17)
Tissue Homogenates (8)
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Strip Plate
Chicken
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Strip Plate
Guinea pig
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Strip Plate
Porcine
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Strip Plate
Monkey
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$728
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 mIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Sandwich
96-Well Microplate
Mouse
0.156 - 10 mU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$929
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$783
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$783
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Custom
96-Well Strip Plate
Rat
Colorimetric - 450nm (TMB)
1 Plate/$783
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Custom
96-Well Strip Plate
Mouse
Colorimetric - 450nm (TMB)
1 Plate/$783
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
78.125 - 5000 U/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Human
0.156 - 10 mU/ml
Chemiluminescent
Plasma, Serum
1 Plate/$728
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Strip Plate
Human
2.5 - 50 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Competitive EIA
96-Well Strip Plate
Rat
2.5 - 50 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Competitive EIA
96-Well Strip Plate
Mouse
0.5 - 10 U/l
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$913
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.156 - 10 mIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.625 - 40 mIU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.31 - 20 mIU/ml
Colorimetric - 450nm (TMB)
Cell Supernatant, Plasma, Serum
1 Plate/$598
GLUD1/Glutamate Dehydrogenase ELISA Kit
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Sandwich
96-Well Strip Plate
Bovine
7.81 - 500 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$889
GLUD1/Glutamate Dehydrogenase ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$818
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).