GLRA2

Glycine Receptor, Alpha 2

Glycine is an important inhibitory transmitter in the brainstem and spinal cord. Glycine receptors are members of the ligand-gated ion channel family (LGICs) that mediate rapid chemical neurotransmission. The binding of glycine to its receptor produces a large increase in chloride conductance, which causes membrane hyperpolarization. Glycine receptors are anchored at inhibitory chemical synapses by a cytoplasmic protein, gephyrin. Gene targeting in mice showed that gephyrin is required for synaptic clustering of glycine receptors in spinal cord. The glycine receptor has been used to great advantage in the identification of the binding sites for alcohol on the LGIC family of proteins. These receptors have also been extremely useful in studies of synaptic clustering of receptors. During postnatal motoneuron development, the glycine receptor alpha subunit changes from alpha2 (fetal) to alpha1 (adult).

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Products

Proteins (11)

Type

Over-Expression Lysate (8)

Recombinant (3)

Target

GLRA2 (11)

Publications

No (11)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (8)

Species

Human (6)

Rat (1)

Source

293T Cells (4)

E. coli (1)

HEK 293 Cells (4)

Wheat Germ Extract (2)

Purification

Purified (1)

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GLRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124397

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

100 µg/$494

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GLRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G124399

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

100 µg/$494

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GLRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129683

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.5 kDa

Price:

100 µg/$494

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Human GLRA2 Protein (Recombinant GST) (Full Length) - LS-G28641

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.49 kDa

Price:

10 µg/$479; 25 µg/$670

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Human GLRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76220

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

20 µg/$150

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Human GLRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76223

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

20 µg/$150

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Human GLRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76221

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

20 µg/$150

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Human GLRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G76222

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

42.5 kDa

Price:

20 µg/$150

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Human GLRA2 Protein (Recombinant GST, N-terminus) (aa151-252) - LS-G58706

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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GLRA2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G99639

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

52 kDa

Price:

100 µg/$494

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Rat GLRA2 Protein (Recombinant) (Lys28-Gln253) - LS-G133732

Source:

E. coli

Tag:

None

Molecular Weight:

29.8kDa

Price:

10 µg/$292; 50 µg/$512; 200 µg/$1,018; 100 µg/$817; 1 mg/$2,168; 500 µg/$1,690; 5 mg/$3,571; 2 mg/$2,359

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