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GLIS2

GLIS family zinc finger 2

GLIS2 is a member of the GLI-similar zinc finger protein family and encodes a nuclear transcription factor with five C2H2-type zinc finger domains. The protein encoded by this gene is widely expressed at low levels in the neural tube and peripheral nervous system and likely promotes neuronal differentiation. It is abundantly expressed in the kidney and may have a role in the regulation of kidney morphogenesis. p120 regulates the expression level of this protein and induces the cleavage of this protein's C-terminal zinc finger domain. This protein also promotes the nuclear translocation of p120. Mutations in this gene cause nephronophthisis (NPHP), an autosomal recessive kidney disease characterized by tubular basement membrane disruption, interstitial lymphohistiocytic cell infiltration, and development of cysts at the corticomedullary border of the kidneys.

Gene Name: GLIS family zinc finger 2
Synonyms: GLIS2, GLI-similar 2, GLI-similar protein 2, GLIS family zinc finger 2, Nephrocystin-7, Neuronal Krueppel-like protein, NKL, NPHP7, Zinc finger protein GLIS2
Target Sequences: NM_032575 NP_115964.2 Q9BZE0

Publications (1)

1
GLIS2 promotes colorectal cancer through repressing enhancer activation. Jie Yao , Pin-Ji Lei , Qing-Lan Li , Ji Chen, Shan-Bo Tang, Qiong Xiao, Xiang Lin, Xiang Wang, Lian-Yun Li, Min Wu. Oncogenesis. 2020 June;9:57. [Full Text Article] [PubMed:32483180] [PMC:PMC7264249] Related Antibodies: LS-C336253.

☰ Filters
Antibodies (16)
Proteins (4)
Over-Expression Lysate (2)
Primary (16)
Recombinant (2)
GLIS2 (20)
Human (16)
Mouse (7)
Rat (7)
Bat (3)
Bovine (3)
Chimpanzee (6)
Dog (3)
Gibbon (6)
Guinea pig (6)
Horse (6)
Monkey (6)
Pig (3)
IHC (1)
WB (16)
ELISA (7)
rabbit (16)
IgG (15)
polyclonal pc (16)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (3)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (5)
aa173-202 (7)
aa183-232 (4)
aa83-132 (4)
No (19)
Yes (1)
GST (1)
His, N-Terminal (1)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
E. coli (1)
HEK 293 Cells (1)
Wheat Germ Extract (1)
Purified (1)
GLIS2 Antibody - Immunohistochemistry of GLIS2 in mouse kidney tissue with GLIS2 antibody at 5 ug/ml.
Select
GLIS2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
0.1 mg/$460
Select
GLIS2 Rabbit anti-Human Polyclonal (aa173-202) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
Select
GLIS2 Rabbit anti-Human Polyclonal (aa173-202) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
GLIS2 Rabbit anti-Human Polyclonal (aa173-202) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
GLIS2 Rabbit anti-Human Polyclonal (aa173-202) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
Select
GLIS2 Rabbit anti-Human Polyclonal (aa173-202) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
Select
GLIS2 Rabbit anti-Human Polyclonal (aa173-202) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
GLIS2 Antibody - A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLIS2 Rabbit anti-Human Polyclonal (aa83-132) Antibody
Human
WB
Unconjugated
100 µl/$397
GLIS2 Antibody - A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLIS2 Rabbit anti-Human Polyclonal (aa83-132) (HRP) Antibody
Mouse, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$442
GLIS2 Antibody - A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLIS2 Rabbit anti-Human Polyclonal (aa83-132) (Biotin) Antibody
Mouse, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$442
GLIS2 Antibody - A: Marker, B: HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLIS2 Rabbit anti-Human Polyclonal (aa83-132) (FITC) Antibody
Mouse, Guinea pig, Rat, Horse, Gibbon, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$442
GLIS2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLIS2 Rabbit anti-Human Polyclonal (aa183-232) Antibody
Human
WB
Unconjugated
100 µl/$424
GLIS2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLIS2 Rabbit anti-Human Polyclonal (aa183-232) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
GLIS2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLIS2 Rabbit anti-Human Polyclonal (aa183-232) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
GLIS2 Antibody - HepG2 Cell Lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
GLIS2 Rabbit anti-Human Polyclonal (aa183-232) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
GLIS2 Antibody - GLIS2 Antibody western blot of NCI-H292 cell line lysates (35 ug/lane). The GLIS2 antibody detected the GLIS2 protein (arrow).
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GLIS2 Rabbit anti-Human Polyclonal (aa173-202) Antibody
Human
WB
Unconjugated
400 µl/$393
GLIS2 Protein - 12.5% SDS-PAGE of human GLIS2 stained with Coomassie Blue
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Wheat Germ Extract
GST
84.59 kDa
2 µg/$439
GLIS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.5 kDa
100 µg/$710
GLIS2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
55.5 kDa
20 µg/$215
GLIS2 Protein
Select
E. coli
His, N-Terminal
55.5 kDa
50 µg/$419
Viewing 1-20 of 20 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).