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Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation.
Gene Name: | GLI family zinc finger 1 |
Synonyms: | GLI1, Gli-1, GLI family zinc finger 1, Glioma-associated oncogene, Glioma-associated oncogene 1, Oncogene GLI, GLI, Zinc finger protein GLI1 |
Target Sequences: | NM_005269 NP_005260.1 P08151 |
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